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ZRSR2 antibody (C-Term)

ZRSR2 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB44050 unconjugated
Catalog No. ABIN1882041
  • Target See all ZRSR2 Antibodies
    ZRSR2 (Zinc Finger (CCCH Type), RNA-Binding Motif and serine/arginine Rich 2 (ZRSR2))
    Binding Specificity
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 453-482, C-Term
    Reactivity
    • 14
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 11
    • 3
    Rabbit
    Clonality
    • 12
    • 2
    Polyclonal
    Conjugate
    • 10
    • 2
    • 1
    • 1
    This ZRSR2 antibody is un-conjugated
    Application
    • 8
    • 7
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This ZRSR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 453-482 amino acids from the C-terminal region of human ZRSR2.
    Clone
    RB44050
    Isotype
    Ig Fraction
  • Application Notes
    WB: 1:1000. IHC-P: 1:25. IHC-P: 1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Expiry Date
    6 months
  • Will, Schneider, Hossbach, Urlaub, Rauhut, Elbashir, Tuschl, Lührmann: "The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome." in: RNA (New York, N.Y.), Vol. 10, Issue 6, pp. 929-41, (2004) (PubMed).

    Scanlan, Gordan, Williamson, Stockert, Bander, Jongeneel, Gure, Jäger, Jäger, Knuth, Chen, Old: "Antigens recognized by autologous antibody in patients with renal-cell carcinoma." in: International journal of cancer. Journal international du cancer, Vol. 83, Issue 4, pp. 456-64, (1999) (PubMed).

    Tronchère, Wang, Fu: "A protein related to splicing factor U2AF35 that interacts with U2AF65 and SR proteins in splicing of pre-mRNA." in: Nature, Vol. 388, Issue 6640, pp. 397-400, (1997) (PubMed).

    Kitagawa, Wang, Hatada, Yamaoka, Nojima, Inazawa, Abe, Mitsuya, Oshimura, Murata: "Isolation and mapping of human homologues of an imprinted mouse gene U2af1-rs1." in: Genomics, Vol. 30, Issue 2, pp. 257-63, (1996) (PubMed).

  • Target
    ZRSR2 (Zinc Finger (CCCH Type), RNA-Binding Motif and serine/arginine Rich 2 (ZRSR2))
    Alternative Name
    ZRSR2 (ZRSR2 Products)
    Synonyms
    ZRSR2 antibody, 35kDa antibody, 5031411E02Rik antibody, A230052C13Rik antibody, C77286 antibody, U2af1-rs2 antibody, URP antibody, RGD1559763 antibody, U2AF1-RS2 antibody, U2AF1L2 antibody, U2AF1RS2 antibody, fb73a09 antibody, wu:fb73a09 antibody, zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2 antibody, zinc finger (CCCH type), RNA binding motif and serine/arginine rich 2 antibody, zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 antibody, ZRSR2 antibody, zrsr2 antibody, ZRSR2Y antibody, Zrsr2 antibody
    Background
    Pre-mRNA-binding protein required for splicing of both U2-and U12-type introns. Selectively interacts with the 3'-splice site of U2-and U12-type pre-mRNAs and promotes different steps in U2 and U12 intron splicing. Recruited to U12 pre-mRNAs in an ATP-dependent manner and is required for assembly of the prespliceosome, a precursor to other spliceosomal complexes. For U2-type introns, it is selectively and specifically required for the second step of splicing.
    Molecular Weight
    58045
    NCBI Accession
    NP_005080
    UniProt
    Q15696
    Pathways
    Ribonucleoprotein Complex Subunit Organization
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