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CDC7 antibody (N-Term)

CDC7 Reactivity: Human WB Host: Rabbit Polyclonal RB3541 unconjugated
Catalog No. ABIN1882165
  • Target See all CDC7 Antibodies
    CDC7 (Cell Division Cycle 7 (CDC7))
    Binding Specificity
    • 16
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 1-30, N-Term
    Reactivity
    • 41
    • 17
    • 12
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 40
    • 1
    Rabbit
    Clonality
    • 38
    • 3
    Polyclonal
    Conjugate
    • 19
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CDC7 antibody is un-conjugated
    Application
    • 15
    • 15
    • 13
    • 13
    • 12
    • 6
    • 6
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This CDC7 (CDC7L1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CDC7 (CDC7L1).
    Clone
    RB3541
    Isotype
    Ig Fraction
    Top Product
    Discover our top product CDC7 Primary Antibody
  • Application Notes
    WB: 1:1000. WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Expiry Date
    6 months
  • Montagnoli, Bosotti, Villa, Rialland, Brotherton, Mercurio, Berthelsen, Santocanale: "Drf1, a novel regulatory subunit for human Cdc7 kinase." in: The EMBO journal, Vol. 21, Issue 12, pp. 3171-81, (2002) (PubMed).

    Hess, Drong, Weiland, Slightom, Sclafani, Hollingsworth: "A human homolog of the yeast CDC7 gene is overexpressed in some tumors and transformed cell lines." in: Gene, Vol. 211, Issue 1, pp. 133-40, (1998) (PubMed).

    Jiang, Hunter: "Identification and characterization of a human protein kinase related to budding yeast Cdc7p." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 26, pp. 14320-5, (1998) (PubMed).

  • Target
    CDC7 (Cell Division Cycle 7 (CDC7))
    Alternative Name
    CDC7 (CDC7L1) (CDC7 Products)
    Synonyms
    CDC7L1 antibody, HsCDC7 antibody, Hsk1 antibody, huCDC7 antibody, AI597260 antibody, Cdc7l1 antibody, muCdc7 antibody, cell division cycle 7 antibody, cell division cycle 7-related protein kinase antibody, cell division cycle 7 (S. cerevisiae) antibody, CDC7 antibody, Tsp_08585 antibody, Cdc7 antibody
    Background
    CDC7L1 is predominantly localized in the nucleus and is a cell division cycle protein with kinase activity. Although expression levels of the protein appear to be constant throughout the cell cycle, the protein kinase activity appears to increase during S phase. It has been suggested that the protein is essential for initiation of DNA replication and that it plays a role in regulating cell cycle progression. Overexpression of this gene product may be associated with neoplastic transformation for some tumors.
    Molecular Weight
    63888
    NCBI Accession
    NP_001127891, NP_001127892, NP_003494
    UniProt
    O00311
    Pathways
    Mitotic G1-G1/S Phases, DNA Replication
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