ERCC1 antibody (C-Term)

Catalog No. ABIN1882194

Product Details anti-ERCC1 Antibody

Target: ERCC1 (Excision Repair Cross Complementing Polypeptide-1 (ERCC1))

Binding Specificity: AA 268-297, C-Term

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ERCC1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.

Immunogen: This ERCC1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 268-297 amino acids from the C-terminal region of human ERCC1.

Clone: 752CT13-2-5

Isotype: IgM kappa

Application Details

Application Notes: WB: 1:2000. WB: 1:1000. WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-ERCC1 antibody (ABIN1882194)

Yu, Mu, Lee, Okamoto, Reed, Bostick-Bruton, Mitchell, Reed: "A nucleotide polymorphism in ERCC1 in human ovarian cancer cell lines and tumor tissues." in: Mutation research, Vol. 382, Issue 1-2, pp. 13-20, (1997) (PubMed).

Hoeijmakers, van Duin, Westerveld, Yasui, Bootsma: "Identification of DNA repair genes in the human genome." in: Cold Spring Harbor symposia on quantitative biology, Vol. 51 Pt 1, pp. 91-101, (1987) (PubMed).

van Duin, de Wit, Odijk, Westerveld, Yasui, Koken, Hoeijmakers, Bootsma: "Molecular characterization of the human excision repair gene ERCC-1: cDNA cloning and amino acid homology with the yeast DNA repair gene RAD10." in: Cell, Vol. 44, Issue 6, pp. 913-23, (1986) (PubMed).

Target Details for ERCC1

Target: ERCC1 (Excision Repair Cross Complementing Polypeptide-1 (ERCC1))

Alternative Name: ERCC1 (ERCC1 Products)

Synonyms: COFS4 antibody, RAD10 antibody, UV20 antibody, Ercc-1 antibody, ercc1 antibody, T12H1.18 antibody, T12H1_18 antibody, UV REPAIR DEFICIENT 7 antibody, UVR7 antibody, ERCC excision repair 1, endonuclease non-catalytic subunit antibody, excision repair cross-complementing rodent repair deficiency, complementation group 1 antibody, DNA excision repair protein ERCC-1 antibody, nucleotide repair protein antibody, excision repair cross-complementation group 1 L homeolog antibody, excision repair cross-complementation group 1 antibody, ERCC1 antibody, Ercc1 antibody, CC1G_04546 antibody, CpipJ_CPIJ013903 antibody, PITG_13719 antibody, ercc1 antibody, ercc1.L antibody

Background: Structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair.

Molecular Weight: 32562

NCBI Accession: NP_001159521, NP_001974, NP_973730

UniProt: P07992

Pathways: DNA Damage Repair, Production of Molecular Mediator of Immune Response