HAGH antibody (C-Term)

Catalog No. ABIN1882252

Product Details anti-HAGH Antibody

Target: HAGH (Hydroxyacylglutathione Hydrolase (HAGH))

Binding Specificity: AA 279-308, C-Term

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HAGH antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Immunogen: This HAGH antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 279-308 amino acids from the C-terminal region of human HAGH.

Clone: 611CT23-6-1

Isotype: IgG1

Application Details

Application Notes: WB: 1:100~1600

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-HAGH antibody (ABIN1882252)

Davila, Froeling, Tan, Bonnard, Boland, Snippe, Hibberd, Seielstad: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, (2010) (PubMed).

Limphong, McKinney, Adams, Bennett, Makaroff, Gunasekera, Crowder: "Human glyoxalase II contains an Fe(II)Zn(II) center but is active as a mononuclear Zn(II) enzyme." in: Biochemistry, Vol. 48, Issue 23, pp. 5426-34, (2009) (PubMed).

Antognelli, Del Buono, Baldracchini, Talesa, Cottini, Brancadoro, Zucchi, Mearini: "Alteration of glyoxalase genes expression in response to testosterone in LNCaP and PC3 human prostate cancer cells." in: Cancer biology & therapy, Vol. 6, Issue 12, pp. 1880-8, (2008) (PubMed).

Antognelli, Baldracchini, Talesa, Costantini, Zucchi, Mearini: "Overexpression of glyoxalase system enzymes in human kidney tumor." in: Cancer journal (Sudbury, Mass.), Vol. 12, Issue 3, pp. 222-8, (2006) (PubMed).

Xu, Chen: "Glyoxalase II, a detoxifying enzyme of glycolysis byproduct methylglyoxal and a target of p63 and p73, is a pro-survival factor of the p53 family." in: The Journal of biological chemistry, Vol. 281, Issue 36, pp. 26702-13, (2006) (PubMed).

Target Details for HAGH

Target: HAGH (Hydroxyacylglutathione Hydrolase (HAGH))

Alternative Name: HAGH (HAGH Products)

Synonyms: glo-2 antibody, glo2 antibody, glx2 antibody, glxii antibody, hagh1 antibody, DDBDRAFT_0186675 antibody, DDBDRAFT_0230988 antibody, DDB_0186675 antibody, DDB_0230988 antibody, DDBDRAFT_0183924 antibody, DDBDRAFT_0230991 antibody, DDB_0183924 antibody, DDB_0230991 antibody, BC019817 antibody, Glo-2 antibody, Glo2 antibody, Rsp29 antibody, RSP29 antibody, fa66a03 antibody, wu:fa66a03 antibody, zgc:73161 antibody, GLO2 antibody, GLX2 antibody, GLXII antibody, HAGH1 antibody, hydroxyacylglutathione hydrolase L homeolog antibody, hydroxyacylglutathione hydrolase antibody, beta-lactamase domain-containing protein antibody, hydroxyacyl glutathione hydrolase antibody, hagh.L antibody, CND02510 antibody, gloB1 antibody, gloB2 antibody, Fbal_1466 antibody, Hagh antibody, hagh antibody, HAGH antibody

Background: The enzyme encoded by this gene is classified as a thiolesterase and is responsible for the hydrolysis of S-lactoyl-glutathione to reduced glutathione and D-lactate. Two transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 33806

NCBI Accession: NP_001035517, NP_005317

UniProt: Q16775