HLAG antibody

Catalog No. ABIN1882254

Product Details anti-HLAG Antibody

Target: HLAG (HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HLAG antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: Purified His-tagged HLA-G protein was used to produced this monoclonal antibody.

Clone: 800CT6-4-2

Isotype: IgG1

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-HLAG antibody (ABIN1882254)

Hampe, Coriton, Andrieux, Carn, Lepourcelet, Mottier, Dréano, Gatius, Hitte, Soriano, Galibert: "A 356-Kb sequence of the subtelomeric part of the MHC Class I region." in: DNA sequence : the journal of DNA sequencing and mapping, Vol. 10, Issue 4-5, pp. 263-99, (2000) (PubMed).

Shukla, Swaroop, Srivastava, Weissman: "The mRNA of a human class I gene HLA G/HLA 6.0 exhibits a restricted pattern of expression." in: Nucleic acids research, Vol. 18, Issue 8, pp. 2189, (1990) (PubMed).

Geraghty, Koller, Orr: "A human major histocompatibility complex class I gene that encodes a protein with a shortened cytoplasmic segment." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 84, Issue 24, pp. 9145-9, (1988) (PubMed).

Target Details for HLAG

Target: HLAG (HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG))

Alternative Name: HLA-G (HLAG Products)

Synonyms: MHC-G antibody, B-F antibody, B-F-S04 antibody, B-F-S05 antibody, B-F-S06 antibody, B-F-S07 antibody, B-FI antibody, B-FIV antibody, BF2 antibody, BFa2 antibody, BFw-03 antibody, BFw-05 antibody, BFz-01 antibody, major histocompatibility complex, class I, G antibody, MHC BF1 class I antibody, HLA-G antibody, BF1 antibody

Background: Involved in the presentation of foreign antigens to the immune system. Plays a role in maternal tolerance of the fetus by mediating protection from the deleterious effects of natural killer cells, cytotoxic T-lymphocytes, macrophages and mononuclear cells.

Molecular Weight: 38224

NCBI Accession: NP_002118

UniProt: P17693

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints