NME1 antibody

Catalog No. ABIN1882270

Product Details anti-NME1 Antibody

Target: NME1 (Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This NME1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: Purified His-tagged NME1 protein was used to produced this monoclonal antibody.

Clone: 1172CT2-4-1-1

Isotype: IgG2a

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:25. IHC-P: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-NME1 antibody (ABIN1882270)

Garcia-Esparcia, Hernández-Ortega, Ansoleaga, Carmona, Ferrer: "Purine metabolism gene deregulation in Parkinson's disease." in: Neuropathology and applied neurobiology, (2015) (PubMed).

Ni, Gu, Dai, Cheng, Guo, Li, Ji, Xie, Ying, Mao: "Isolation and characterization of a novel human NM23-H1B gene, a different transcript of NM23-H1." in: Journal of human genetics, Vol. 48, Issue 2, pp. 96-100, (2003) (PubMed).

Dooley, Seib, Engel, Theisinger, Janz, Piontek, Zang, Welter: "Isolation and characterization of the human genomic locus coding for the putative metastasis control gene nm23-H1." in: Human genetics, Vol. 93, Issue 1, pp. 63-6, (1994) (PubMed).

Gilles, Presecan, Vonica, Lascu: "Nucleoside diphosphate kinase from human erythrocytes. Structural characterization of the two polypeptide chains responsible for heterogeneity of the hexameric enzyme." in: The Journal of biological chemistry, Vol. 266, Issue 14, pp. 8784-9, (1991) (PubMed).

Rosengard, Krutzsch, Shearn, Biggs, Barker, Margulies, King, Liotta, Steeg: "Reduced Nm23/Awd protein in tumour metastasis and aberrant Drosophila development." in: Nature, Vol. 342, Issue 6246, pp. 177-80, (1989) (PubMed).

Target Details for NME1

Target: NME1 (Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))

Alternative Name: NME1 (NME1 Products)

Synonyms: AWD antibody, GAAD antibody, NB antibody, NBS antibody, NDKA antibody, NDPK-A antibody, NDPKA antibody, NM23 antibody, NM23-H1 antibody, AL024257 antibody, NM23-M1 antibody, NM23A antibody, NDPK-Z1 antibody, NM23-B antibody, NM23-Z1 antibody, ndpkz1 antibody, nm23b antibody, nme1 antibody, nme2 antibody, nme2b1 antibody, NME1 antibody, NME1-NME2 antibody, NM23-C1 antibody, ndpk-b antibody, ndpkb antibody, nm23-h2 antibody, nm23ndk antibody, puf antibody, NBR-A antibody, NBR-B antibody, NME1-1 antibody, nm23ndk-a antibody, NDK I antibody, NDPK I antibody, T30A10.80 antibody, T30A10_80 antibody, NDP kinase I antibody, NME/NM23 nucleoside diphosphate kinase 1 antibody, NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 1 antibody, non-metastatic cells 1, protein (NM23A) expressed in antibody, NME/NM23 nucleoside diphosphate kinase 2 S homeolog antibody, NME/NM23 nucleoside diphosphate kinase 2 L homeolog antibody, nucleoside diphosphate kinase antibody, nucleoside diphosphate kinase 1 antibody, NME1 antibody, Nme1 antibody, nme2b.1 antibody, nme2.S antibody, nme2.L antibody, LOC547870 antibody, NDPK1 antibody, LOC107790563 antibody

Background: Major role in the synthesis of nucleoside triphosphates other than ATP. Possesses nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3'-5' exonuclease activities. Involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression. Required for neural development including neural patterning and cell fate determination.

Molecular Weight: 17149

NCBI Accession: NP_000260, NP_937818

UniProt: P15531

Pathways: Apoptosis, Nucleotide Phosphorylation, Carbohydrate Homeostasis, Ribonucleoside Biosynthetic Process