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5-HT (Serotonin) antibody

Details for Product No. ABIN188515, Supplier: Log in to see
Antigen
Reactivity
Mouse (Murine)
3
2
1
1
Host
Rabbit
6
1
Clonality
Polyclonal
Application
Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
7
5
4
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Cross-Reactivity Mouse (Murine), Rat (Rattus)
Purification Serum
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Restrictions For Research Use only
Format Liquid
Storage RT
Product cited in: Yadav, Kroeze, Farrell et al.: "ANTAGONIST FUNCTIONAL SELECTIVITY: 5-HT2A SEROTONIN RECEPTOR ANTAGONISTS DIFFERENTIALLY REGULATE 5-HT2A RECEPTOR PROTEIN LEVEL IN VIVO." in: The Journal of pharmacology and experimental therapeutics, 2011 (PubMed).

Yadav, Abbas, Farrell et al.: "The presynaptic component of the serotonergic system is required for clozapine's efficacy." in: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, Vol. 36, Issue 3, pp. 638-51, 2011 (PubMed).

Schmid, Bohn: "Serotonin, but not N-methyltryptamines, activates the serotonin 2A receptor via a ß-arrestin2/Src/Akt signaling complex in vivo." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 40, pp. 13513-24, 2010 (PubMed). (1:133). Further details: The 5-HT 2A R was immunoprecipitated from equivalent aliquots of remaining lysates by overnight incubation with a polyclonal rabbit antibody against the N terminus of the 5-HT2AR at 4�C, complexes were immobilized on Protein A Sepharose

Magalhaes, Holmes, Dale et al.: "CRF receptor 1 regulates anxiety behavior via sensitization of 5-HT2 receptor signaling." in: Nature neuroscience, Vol. 13, Issue 5, pp. 622-9, 2010 (PubMed).