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5-Hydroxytryptamine (5-HT) antibody

Details for Product No. ABIN188515, Supplier: Log in to see
Antigen
Reactivity
Mouse (Murine)
44
32
24
10
10
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Host
Rabbit
67
14
12
8
4
Clonality
Polyclonal
Conjugate
Un-conjugated
2
2
1
Application
Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
44
37
33
28
19
12
7
4
4
3
3
2
2
1
1
1
1
1
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Cross-Reactivity Mouse (Murine), Rat (Rattus)
Purification Serum
Alternative Name 5-HT (Serotonin)
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Restrictions For Research Use only
Format Liquid
Storage RT
Product cited in: Yadav, Kroeze, Farrell, Roth: "ANTAGONIST FUNCTIONAL SELECTIVITY: 5-HT2A SEROTONIN RECEPTOR ANTAGONISTS DIFFERENTIALLY REGULATE 5-HT2A RECEPTOR PROTEIN LEVEL IN VIVO." in: The Journal of pharmacology and experimental therapeutics, 2011

Yadav, Abbas, Farrell, Setola, Sciaky, Huang, Kroeze, Crawford, Piel, Keiser, Irwin, Shoichet, Deneris, Gingrich, Beck, Roth: "The presynaptic component of the serotonergic system is required for clozapine's efficacy." in: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, Vol. 36, Issue 3, pp. 638-51, 2011

Schmid, Bohn: "Serotonin, but not N-methyltryptamines, activates the serotonin 2A receptor via a ß-arrestin2/Src/Akt signaling complex in vivo." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 40, pp. 13513-24, 2010 (1:133). Further details: The 5-HT 2A R was immunoprecipitated from equivalent aliquots of remaining lysates by overnight incubation with a polyclonal rabbit antibody against the N terminus of the 5-HT2AR at 4�C, complexes were immobilized on Protein A Sepharose

Magalhaes, Holmes, Dale, Comps-Agrar, Lee, Yadav, Drysdale, Poulter, Roth, Pin, Anisman, Ferguson: "CRF receptor 1 regulates anxiety behavior via sensitization of 5-HT2 receptor signaling." in: Nature neuroscience, Vol. 13, Issue 5, pp. 622-9, 2010