Serotonin receptor 2A (HTR2A) antibody

Antigen: Serotonin receptor 2A (HTR2A)

Clonality: Polyclonal

Host: Rabbit

Reactivity: Mouse (Murine), Rat (Rattus)

Application: Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Western Blotting (WB)

Catalog no.: ABIN188515

Additional Information

Format: Serum

Application Details

Restrictions: For Research Use only

Publications

Publications: Magalhaes, Holmes, Dale et al.: "CRF receptor 1 regulates anxiety behavior via sensitization of 5-HT2 receptor signaling." in: Nature neuroscience, Vol. 13, Issue 5, pp. 622-9, 2010 (PubMed).

Schmid, Bohn: "Serotonin, but not N-methyltryptamines, activates the serotonin 2A receptor via a ß-arrestin2/Src/Akt signaling complex in vivo." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 40, pp. 13513-24, 2010 (PubMed). (1:133). Further details: The 5-HT 2A R was immunoprecipitated from equivalent aliquots of remaining lysates by overnight incubation with a polyclonal rabbit antibody against the N terminus of the 5-HT2AR at 4�C, complexes were immobilized on Protein A Sepharose

Yadav, Abbas, Farrell et al.: "The presynaptic component of the serotonergic system is required for clozapine's efficacy." in: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, Vol. 36, Issue 3, pp. 638-51, 2011 (PubMed).

Yadav, Kroeze, Farrell et al.: "ANTAGONIST FUNCTIONAL SELECTIVITY: 5-HT2A SEROTONIN RECEPTOR ANTAGONISTS DIFFERENTIALLY REGULATE 5-HT2A RECEPTOR PROTEIN LEVEL IN VIVO." in: The Journal of pharmacology and experimental therapeutics, 2011 (PubMed).