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AKR1C1 antibody (AA 22-218)
DDH
Reactivity: Human
WB, IHC, IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-AKR1C1 Antibody
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Target
See all AKR1C1 (DDH) Antibodies
AKR1C1 (DDH)
(Dihydrodiol Dehydrogenase (DDH))
Binding Specificity
All epitopes for AKR1C1 antibodies
AA 22-218
Reactivity
All reactivities for AKR1C1 antibodies
Human
Host
All hosts for AKR1C1 antibodies
Rabbit
Clonality
All clonalities for AKR1C1 antibodies
Polyclonal
Conjugate
All conjugates for AKR1C1 antibodies
This AKR1C1 antibody is un-conjugated
Application
All applications for AKR1C1 antibodies
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Purification
Purified by antigen-affinity chromatography.
Immunogen
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 22 and 218 of Human AKR1C1
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Alternatives
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Application Details
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Application Notes
Suggested dilutions: Western blotting: 1.500-1.3000 Immunohistochemistry: 1.50-1.500 Immunofluorescence: 1.100-1.200
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
Preservative
Thimerosal (Merthiolate)
Precaution of Use
Biohazard Informations: This product contains thimerosal which is hazardous.
Storage
4 °C/-20 °C
Storage Comment
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Target Details for AKR1C1
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Target
AKR1C1 (DDH)
(Dihydrodiol Dehydrogenase (DDH))
Alternative Name
AKR1C1 (DDH Products )
Synonyms
2-ALPHA-HSD antibody, 20-ALPHA-HSD antibody, C9 antibody, DD1 antibody, DD1/DD2 antibody, DDH antibody, DDH1 antibody, H-37 antibody, HAKRC antibody, HBAB antibody, MBAB antibody, aldo-keto reductase family 1 member C1 antibody, aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) antibody, AKR1C1 antibody
Background
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins.These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors.The enzymes display overlapping but distinct substrate.This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone.This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.[provided by RefSeq]
Molecular Weight
37 kDa
Gene ID
1645
NCBI Accession
NP_001344 , NM_001353
Pathways
Steroid Hormone Biosynthesis , C21-Steroid Hormone Metabolic Process
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