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AKR1C1 antibody (AA 22-218)

DDH Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1886214
  • Target See all AKR1C1 (DDH) Antibodies
    AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))
    Binding Specificity
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 22-218
    Reactivity
    • 34
    • 12
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 28
    • 6
    Rabbit
    Clonality
    • 31
    • 3
    Polyclonal
    Conjugate
    • 23
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AKR1C1 antibody is un-conjugated
    Application
    • 21
    • 11
    • 10
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein fragment contain a sequence corresponding to a region within amino acids 22 and 218 of Human AKR1C1
    Top Product
    Discover our top product DDH Primary Antibody
  • Application Notes
    Suggested dilutions:
    Western blotting: 1.500-1.3000
    Immunohistochemistry: 1.50-1.500
    Immunofluorescence: 1.100-1.200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    Biohazard Informations: This product contains thimerosal which is hazardous.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Target
    AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))
    Alternative Name
    AKR1C1 (DDH Products)
    Synonyms
    2-ALPHA-HSD antibody, 20-ALPHA-HSD antibody, C9 antibody, DD1 antibody, DD1/DD2 antibody, DDH antibody, DDH1 antibody, H-37 antibody, HAKRC antibody, HBAB antibody, MBAB antibody, aldo-keto reductase family 1 member C1 antibody, aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) antibody, AKR1C1 antibody
    Background
    This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins.These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors.The enzymes display overlapping but distinct substrate.This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone.This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.[provided by RefSeq]
    Molecular Weight
    37 kDa
    Gene ID
    1645
    NCBI Accession
    NP_001344, NM_001353
    Pathways
    Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process
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