GLDC antibody (AA 442-693)

Catalog No. ABIN1886475

Product Details anti-GLDC Antibody

Target: GLDC (Glycine Dehydrogenase (GLDC))

Binding Specificity: AA 442-693

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLDC antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 442 and 693 of Human GLDC

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.50-1.500
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for GLDC

Target: GLDC (Glycine Dehydrogenase (GLDC))

Alternative Name: Glycine dehydrogenase (GLDC Products)

Synonyms: PSPTO1276 antibody, Tb07.43M14.350 antibody, DDBDRAFT_0219205 antibody, DDBDRAFT_0231130 antibody, DDB_0219205 antibody, DDB_0231130 antibody, D030049L12Rik antibody, D19Wsu57e antibody, GCE antibody, GCSP antibody, HYGN1 antibody, fb23b05 antibody, wu:fb23b05 antibody, zgc:66198 antibody, gldc antibody, glycine dehydrogenase (decarboxylating) GcvP antibody, glycine dehydrogenase antibody, glycine cleavage system P-protein antibody, glycine decarboxylase antibody, glycine dehydrogenase (decarboxylating) antibody, glycine decarboxylase S homeolog antibody, gcvP antibody, Tb927.7.1910 antibody, Gldc antibody, GLDC antibody, gldc antibody, gldc.S antibody

Background: The enzyme system for cleavage of glycine (glycine cleavage system, GCS, EC 2.1.2.10), which is confined to the mitochondria, is composed of 4 protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase).Glycine encephalopathy (GCE, MIM 605899) may be due to a defect in any one of these enzymes, see MIM 238310, MIM 238330, and MIM 238331.[supplied by OMIM]

Molecular Weight: 113 kDa

Gene ID: 2731

NCBI Accession: NM_000170, NP_000161