LTBP4 antibody (AA 64-256)

Catalog No. ABIN1886594

Product Details anti-LTBP4 Antibody

Target: LTBP4 (Latent Transforming Growth Factor beta Binding Protein 4 (LTBP4))

Binding Specificity: AA 64-256

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LTBP4 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 64 and 256 of LTBP-4

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 1 x PBS, 1 % BSA, 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for LTBP4

Target: LTBP4 (Latent Transforming Growth Factor beta Binding Protein 4 (LTBP4))

Alternative Name: LTBP-4 (LTBP4 Products)

Synonyms: ARCL1C antibody, LTBP-4 antibody, LTBP4L antibody, LTBP4S antibody, 2310046A13Rik antibody, latent transforming growth factor beta binding protein 4 antibody, LTBP4 antibody, ltbp4 antibody, Ltbp4 antibody

Background: Transforming growth factor-beta, or TGFB (see TGFB1, MIM 190180), remains biologically latent after secretion, blocked from activity by its N-terminal propeptide (the latency-associated peptide, or LAP).TGFB is activated by its dissociation from LAP.The latent form of TGFB is secreted in association with a latent TGFB-binding protein, or LTBP (see LTBP1, MIM 150390), and assembled into the extracellular matrix.LTBPs are mainly composed of epidermal growth factor (EGF, MIM 131530)-like repeats and protein domains with 8-cysteine repeats, both of which are also found in fibrillins (e.g., MIM 134797).See Oklu and Hesketh (2000) [PubMed 11104663] for a review of the LTBP gene family.[supplied by OMIM]

Molecular Weight: 169 kDa

Gene ID: 8425

NCBI Accession: NM_003573, NP_003564

Pathways: Hormone Transport, Growth Factor Binding