Klra3 antibody (C-Term)

Catalog No. ABIN1886992

Product Details anti-Klra3 Antibody

Target: Klra3 (Killer Cell Lectin-Like Receptor, Subfamily A, Member 3 (Klra3))

Binding Specificity: C-Term

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Klra3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity (Details): This antibody may cross-react with other LY49 receptors.

Purification: Affinity chromatography purified via peptide column

Immunogen: 14 amino acid peptide near the carboxy terminus of mouse KLRA3.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for Klra3

Target: Klra3 (Killer Cell Lectin-Like Receptor, Subfamily A, Member 3 (Klra3))

Alternative Name: KLRA3 (Klra3 Products)

Synonyms: 5E6 antibody, Ly49c antibody, NK-2.1 antibody, Nk-2 antibody, Nk2 antibody, Nk2.1 antibody, killer cell lectin-like receptor, subfamily A, member 3 antibody, Klra3 antibody

Background: KLRA3 (also known as Ly49C) is a member of the LY49 family of receptors in Natural Killer (NK) cells that bind to major histocompatibility complex (MHC) class 1.These proteins are classified as either activating or inhibitory receptors based on whether they possess an immunoreceptor tyrosine-based inhibitory motif (ITIM) in their cytoplasmic region (for inhibitory receptors), or an immunoreceptor tyrosine-based activation motif (ITAM) that transmits activating signals resulting in phosphorylation of several substrates.KLRA3 is thought to be an inhibitory receptor, recognizing peptide -receptive H-2Kb.
Synonyms: Killer cell lectin-like receptor subfamily A member 3, Ly49C, Nk2