GBP6 antibody (C-Term)

Catalog No. ABIN1887047

Product Details anti-GBP6 Antibody

Target: GBP6 (Guanylate Binding Protein 6 (GBP6))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GBP6 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Cross-Reactivity (Details): GBP6 antibody is predicted to not cross-react with other GBP family members.

Purification: Affinity chromatography purified via peptide column

Immunogen: 15 amino acid peptide near the carboxy terminus of human GBP6.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for GBP6

Target: GBP6 (Guanylate Binding Protein 6 (GBP6))

Alternative Name: GBP6 (GBP6 Products)

Synonyms: AI595338 antibody, Mpa2l antibody, guanylate binding protein 6 antibody, guanylate binding protein family member 6 antibody, Gbp6 antibody, GBP6 antibody

Background: The guanylate-binding proteins (GBPs), a family of interferon-induced GTP-binding proteins function in innate immunity against microbial and viral pathogens.In humans, there are seven GBPs from hGBP1 to hGBP7.Human GBP1 and GBP2 have been shown to exhibit antiviral activity as well as being able to regulate the inhibition of proliferation and invasion of endothelial cells in response to interferon (IFN) (1,3).GBP6 is induced by IFN and hydrolyzes GTP to both GDP and GMP.The precise function of GBP6 is still under investigation .
Synonyms: Guanylate binding protein family member 6, GTP-binding protein 6, Guanine nucleotide-binding protein 6, GBP-6

NCBI Accession: NP_940862

Pathways: Cellular Response to Molecule of Bacterial Origin