ST3GAL6 antibody (C-Term)

Catalog No. ABIN1887120

Product Details anti-ST3GAL6 Antibody

Target: ST3GAL6 (ST3 beta-Galactoside alpha-2,3-Sialyltransferase 6 (ST3GAL6))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ST3GAL6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Purification: Affinity chromatography purified via peptide column

Immunogen: 16 amino acid peptide from near the carboxy terminus of human ST3gal6.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for ST3GAL6

Target: ST3GAL6 (ST3 beta-Galactoside alpha-2,3-Sialyltransferase 6 (ST3GAL6))

Alternative Name: ST3gal6 (ST3GAL6 Products)

Synonyms: SIAT10 antibody, ST3GALVI antibody, 1700023B24Rik antibody, AI930218 antibody, AW552396 antibody, Siat10 antibody, St3galVI antibody, ST3GAL-VI antibody, ST3 beta-galactoside alpha-2,3-sialyltransferase 6 antibody, ST3GAL6 antibody, St3gal6 antibody

Background: Sialyltransferases catalyze the transfer of sialic acid from cytidine 5-prime monophospho-N-acetylneuraminic acid (CMP-NeuAc) to terminal positions of glycoprotein and glycolipid carbohydrate groups.Terminal NeuAc residues are key determinants of carbohydrate structures, such as the sialyl-Lewis X determinants, and are widely distributed in many cell types.However, cancer cells often express more heavily sialylated glycans on their cell surface and this feature sometimes correlates with invasiveness.In contrast, expression of ST3gal6, a member of the sialyltransferase family that sialylates type II lactosamine structures on glycoproteins and glycolipids, was found to be significantly decreased by hypermethylation of the gene in gastrointestinal cancer.At least three isoforms of ST3gal6 are known to exist.
Synonyms: Alpha2, 3-sialyltransferase 6, ST3Gal VI, siat10

NCBI Accession: NP_006091

Pathways: Glycosaminoglycan Metabolic Process