MYZAP antibody (C-Term)

Catalog No. ABIN1887247

Product Details anti-MYZAP Antibody

Target: MYZAP (Myocardial Zonula Adherens Protein (MYZAP))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYZAP antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: Multiple isoforms of MYOZAP are known to exist.

Purification: Affinity chromatography purified via peptide column

Immunogen: 18 amino acid peptide near the carboxy terminus of human MYOZAP.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for MYZAP

Target: MYZAP (Myocardial Zonula Adherens Protein (MYZAP))

Alternative Name: MYOZAP (MYZAP Products)

Synonyms: AA407270 antibody, AV006038 antibody, Gcom1 antibody, Gm640 antibody, Grinl1a7 antibody, Myozap antibody, Myzap antibody, GLURR2 antibody, GRINL1B antibody, GCOM1 antibody, Gup antibody, Gup1 antibody, Gup2 antibody, MYOZAP antibody, myocardial zonula adherens protein antibody, GRINL1B complex locus 2 (pseudogene) antibody, Myzap antibody, GCOM2 antibody, MYZAP antibody

Background: MYOZAP, also known as GRINL1A, is a 54 kDa highly conserved cardiac protein.It is strongly expressed in the heart and lung and is a novel component of intercalated disc.MYOZAP interacts with myosin phosphatase-RhoA interacting protein (MRIP) and acts as an activator of Rho-dependent SRF signaling.Knockdown study in zebrafish results in cardiomyopathy with severe dysfunction.The MYOZAP gene is part of a complex transcript unit that includes the gene for glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A (GRINL1A).Transcription of this gene occurs at an upstream promoter, with two different groups of alternatively spliced variants: Gup for GRINL1A upstream transcripts and Gcom for GRINL1A combined transcripts.
Synonyms: Myocardium-enriched zonula occludens-1

NCBI Accession: NP_001018110