SEC16B antibody (C-Term)

Catalog No. ABIN1887350

Product Details anti-SEC16B Antibody

Target: SEC16B (SEC16 Homolog B (SEC16B))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SEC16B antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Affinity chromatography purified via peptide column

Immunogen: LZTR2 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human LZTR2.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for SEC16B

Target: SEC16B (SEC16 Homolog B (SEC16B))

Alternative Name: LZTR2 (SEC16B Products)

Synonyms: LZTR2 antibody, PGPR-p117 antibody, RGPR antibody, SEC16S antibody, Lztr2 antibody, Rgpr antibody, Rgpr-p117 antibody, RGPR-p117 antibody, SEC16 homolog B, endoplasmic reticulum export factor antibody, SEC16 homolog B (S. cerevisiae) antibody, SEC16B antibody, sec16b antibody, Sec16b antibody

Background: LZTR2, also known as RGPR-p117, is a member of the BTB-kelch superfamily and was initially described as a nuclear factor I (NFI) binding protein and transcriptional regulator of the regucalcin gene.LZTR2 is cytoplasmically localized but is thought to translocate to the nucleus, a process mediated by protein kinase C signaling following hormonal stimulation.Recent evidence has suggested that there is a strong correlation of single nucleotide polymorphisms of LZTR2 with obesity in the Japanese population similar to that seen with the TMEM18 gene and the GNPDA2, BDNF, FAIM2, and MC4R genes with obesity in Caucasian populations, suggesting LZTR2 may play a role in metabolism and obesity risk.
Synonyms: Leucine zipper-like transcription regulator 2, SEC16B, RGPR, RGPR-p117

NCBI Accession: NP_149118