EFCAB4A antibody (Center)

Catalog No. ABIN1887557

Product Details anti-EFCAB4A Antibody

Target: EFCAB4A (EF-Hand Calcium Binding Domain 4A (EFCAB4A))

Binding Specificity: Center

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EFCAB4A antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Affinity chromatography purified via peptide column

Immunogen: 15 amino acid peptide near the center of human EFCAB4A.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for EFCAB4A

Target: EFCAB4A (EF-Hand Calcium Binding Domain 4A (EFCAB4A))

Alternative Name: EFCAB4A (EFCAB4A Products)

Synonyms: CRACR2B antibody, 6330520A15Rik antibody, BC026645 antibody, Cracr2a antibody, Efcab4 antibody, RGD1560911 antibody, zgc:158448 antibody, calcium release activated channel regulator 2B antibody, cracr2b antibody, CRACR2B antibody, Cracr2b antibody

Background: EFCAB4A, also known as Calcium release-activated calcium channel regulator 2B, is a novel Ca2+-binding EF-hand protein that is thought to play a key role in store-operated Ca2+ entry in T-cells by regulating CRAC channel activation, but the detailed function is still under investigation.It is likely to play a similar role as the related protein EFCAB4B, which acts as a cytoplasmic calcium-sensor that forms a complex with ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca2+ concentration.
Synonyms: EF-hand calcium binding domain 4A, Calcium release-activated calcium channel regulator 2, CRACR2B

NCBI Accession: NP_775855