SLC39A12 antibody (N-Term)

Catalog No. ABIN1887947

Product Details anti-SLC39A12 Antibody

Target: SLC39A12 (Solute Carrier Family 39 (Zinc Transporter), Member 12 (SLC39A12))

Binding Specificity: N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC39A12 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity (Details): At least four isoforms of ZIP12 are known to exist. ZIP12 antibody is predicted to not cross-react with other ZIP family members.

Purification: Affinity chromatography purified via peptide column

Immunogen: 15 amino acid peptide near the amino terminus of human ZIP12.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for SLC39A12

Target: SLC39A12 (Solute Carrier Family 39 (Zinc Transporter), Member 12 (SLC39A12))

Alternative Name: ZIP12 (SLC39A12 Products)

Synonyms: LZT-Hs8 antibody, ZIP-12 antibody, bA570F3.1 antibody, AW046938 antibody, Gm731 antibody, solute carrier family 39 member 12 antibody, solute carrier family 39 (zinc transporter), member 12 antibody, SLC39A12 antibody, Slc39a12 antibody, slc39a12 antibody

Background: The zinc transporter ZIP12, also known as SLC39A12, is a member of a family of divalent ion transporters.Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation.The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA).ZIP12 is a multipass membrane protein that belongs to the ZIP transporter subfamily LIV-1.Increased levels of ZIP12 have been observed during acute inflammation in the airway and asthma, suggesting that it may be promote increased zinc uptake, as this can reduce inflammation.The zinc content in brains in individuals with schizophrenia is lower than in individuals with other cerebral diseases, and mutations in ZIP12 have been observed in a small group of schizophrenic patients, suggesting that ZIP12 may play a role in this disease.
Synonyms: Solute carrier family 39 member A12, Slc39A12, LZT-Hs8

NCBI Accession: NP_001138667