PCDH12 antibody (N-Term)

Catalog No. ABIN1888050

Product Details anti-PCDH12 Antibody

Target: PCDH12 (Protocadherin 12 (PCDH12))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCDH12 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity (Details): This antibody is predicted to not cross-react with PCDH18.

Purification: Affinity chromatography purified via peptide column

Immunogen: 17 amino acid peptide near the amino terminus of human PCDH12.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for PCDH12

Target: PCDH12 (Protocadherin 12 (PCDH12))

Alternative Name: PCDH12 (PCDH12 Products)

Synonyms: PCDH12 antibody, VE-cadherin-2 antibody, VECAD2 antibody, Pcdh14 antibody, VE-cad-2 antibody, protocadherin 12 antibody, PCDH12 antibody, Pcdh12 antibody

Background: Protocadherins comprise the largest group within the cadherin family of calcium-dependent cell-cell adhesion molecules.Protocadherin 12 (PCDH12) was initially identified through PCR screening of mouse heart microvascular endothelial cell RNA, further experiments revealed its mRNA to be strongly expressed in highly vascularized organs such as lung and kidney, in addition to glycogen-rich trophoblasts in the placenta.PCDH12-null mice are viable and fertile, but show reduced placental and embryonic sizes when compared to wild-type mice.Further studies showed significant expression changes in 2, 289 genes, including those involved in tissue morphogenesis, angiogenesis, cell-matrix adhesion and migration, immune response and chromatin remodeling.
Synonyms: Protocadherin 12, vascular endothelial cadherin 2, VE-cadherin 2, VECAD2

NCBI Accession: NP_057664

Pathways: Cellular Glucan Metabolic Process