CADPS antibody (N-Term)

Catalog No. ABIN1888141

Product Details anti-CADPS Antibody

Target: CADPS (Ca++-Dependent Secretion Activator (CADPS))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CADPS antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Specificity: Numerous isoforms of CAPS1 are known to exist.This CAPS1 antibody is predicted to be specific to CAPS1 and not recognize CAPS2.

Purification: Affinity chromatography purified via peptide column

Immunogen: 21 amino acid peptide near the amino terminus of the human CAPS1.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for CADPS

Target: CADPS (Ca++-Dependent Secretion Activator (CADPS))

Alternative Name: CAPS1 (CADPS Products)

Synonyms: CADPS1 antibody, CAPS antibody, CAPS1 antibody, Caps antibody, Caps1 antibody, Caps2 antibody, AU067781 antibody, mKIAA1121 antibody, CADPS antibody, cadps antibody, MGC122552 antibody, CAPS-1 antibody, caps antibody, caps1 antibody, si:busm1-1i3.1 antibody, si:busm1-6a2.7 antibody, si:dz6a2.7 antibody, calcium dependent secretion activator antibody, Ca2+-dependent secretion activator antibody, Ca2+-dependent activator protein for secretion b antibody, Ca2+ dependent secretion activator antibody, Ca2+ dependent secretion activator L homeolog antibody, Ca2+-dependent activator protein for secretion a antibody, CADPS antibody, Cadps antibody, cadpsb antibody, cadps antibody, cadps.L antibody, cadpsa antibody

Background: CAPS1 and its related protein CAPS2 encode novel neural/endocrine-specific cytosolic and peripheral membrane proteins.Both are essential components of the synaptic vesicle priming machinery and are required for the Ca2+-regulated exocytosis of secretory vesicles, CAPS-deficienct neurons contain no or very few fusion competent synaptic vesicles, causing a selective impairment of fast phasic transmitter release.CAPS1 acts at a stage in exocytosis that follows ATP-dependent priming, which involves the essential synthesis of phosphatidylinositol 4, 5-bisphosphate and is thought to be a specific regulator of large dense-core vesicle fusion.
Synonyms: Calcium-dependent secretion activator 1, CADPS1, CAPS?

NCBI Accession: NP_899631

Pathways: Synaptic Vesicle Exocytosis