PRICKLE4
Reactivity: Human
ELISA
Host: Rabbit
Polyclonal
FITC
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS containing 0.02 % sodium azide.
Preservative
Sodium azide
Precaution of Use
WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handling Advice
Avoid freezing and thawing repeatly.
Storage
4 °C/-20 °C
Storage Comment
Store at 4 °C for short term use.Store at -20 °C for long term preservation.
PRICKLE4, also known as over-expressed breast tumor protein (OBTP), is a member of the LIM family of proteins.It possesses two LIM domains as well as a PET domain and is thought to localize to the nucleus.Its expression in multiple malignant tissue differentiations indicate that it may play a role in cancer differentiation.Two other members of the LIM family, PRICKLE1 and PRICKLE2, are thought to function in the noncanonical WNT signaling pathway which regulates intracellular calcium release and planar cell polarity, suggesting the PRICKLE4 may play a similar role. Synonyms: REST, NRSF-interacting LIM domain protein 4, OBTP, OEBT, TOMM6, C6orf49