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Caveolin 1, Caveolae Protein, 22kDa (CAV1) (C-Term) antibody
| Antigen | Caveolin 1, Caveolae Protein, 22kDa (CAV1) |
| Synonyms | CAV, CGL3, BSCL3, VIP21, MSTP085, Cav, Cav-1, MGC187299, CAV1, fc07c04, wu:fc07c04, cav1a, cav1b, caveolin 1, cav, vip21, mstp085, MGC107940, Caveolin-1, cav1 |
| Epitope |
 Alternatives C-Term |
| Clonality | Monoclonal (E249) |
| Host |
Alternatives Rabbit |
| Reactivity |
Alternatives Human, Mouse (Murine) |
| Application |
Alternatives Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
|
| Catalog no. | ABIN189214 |
| Quantity | 0.1 ml |
| Price | Product not available in this region. |
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Additional Information
| Alternative name | Caveolin-1 (C-term) |
| Gene ID | 857, 12389 |
| Swiss-Prot | Q03135 |
| Isotype | IgG (Matching secondary antibodies) |
| Clone | E249 |
| Description | Caveolins make up a family of proteins that are principal structural components ofhairpin-like domains in the plasma membrane (1). It is believed that caveolins serve asscaffolding proteins for the integration of signal transduction. Three members ofcaveolins (caveolin-1, -2 and -3) have been identified, possessing different tissuedistributions (2). Caveolins interact with multiple signaling molecules, such as theG-protein alpha subunit (1), tyrosine kinase receptors, PKCs, Src family tyrosine kinasesand eNOS (2,3). Caveolin-1 has been implicated in the pathogenesis of mammaryepithelial cell hyperplasia (4). Alternate Names: anti-CAV 1 antibody, anti-CAV antibody, anti-CAV1 antibody, anti-Caveolin 1 caveolaeprotein 22kDa antibody, anti-Caveolin1 antibody, anti-MSTP085 antibody, anti-VIP 21antibody, anti-VIP21 antibody. |
| Specificity | A synthetic peptide corresponding to residues near C-terminus of human Caveolin-1was used as immunogen. The antibody should recognize both alpha and beta form ofCaveolin-1. Species Reactivity: Cross reacts with Human and Mouse. |
Application Details
| Application Notes | Suggested working dilutions: immunohistochemistry 1:250,Western Blot 1:20000,Immunocytochemistry 1:100 |
| Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, and 0.05% BSA. Preservative: 0.01% sodium azide. |
| Storage | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Restrictions | For Research Use only |
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Alternatives
Alternatives for antigen "Caveolin 1, Caveolae Protein, 22kDa (CAV1)", type "Antibodies"
| Hosts | Rabbit (69), Goat (8), Mouse (6), Sheep (2) |
| Reactivities | Human (73), Rat (Rattus) (52), Mouse (Murine) (50), Dog (Canine) (6), Pig (Porcine) (5), Hamster (1) |
| Applications | Western Blotting (WB) (53), Immunofluorescence (IF) (22), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (21), Flow Cytometry (FACS) (13), Enzyme Immunoassay (EIA) (12), ELISA (11), Immunohistochemistry (IHC) (6), Immunoprecipitation (IP) (6), Dot Blot (Dot) (2), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), ELISA (Detection) (1), Immunocytochemistry (ICC) (1), Immunoelectron Microscopy (EM) (1) |
| Conjugates | Alexa Flour 488 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1), RBITC (1) |
| Epitopes | pTyr14 (10), N-Term (8), C-Term (5), 1t cytoplasmic domain (4), internal (2), Y14 (1), non pTyr14 (1), pY14 (1) |
