GABRA6 antibody (AA 15-26)

Catalog No. ABIN1897186

Product Details anti-GABRA6 Antibody

Target: GABRA6 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 6 (GABRA6))

Binding Specificity: AA 15-26

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This GABRA6 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Brand: IHC-plus™

Specificity: Human GABRA6

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide ENALGKLEVEGN-C from the N-terminus of human GABRA6 (NP_000802.2). Percent identity by BLAST analysis: Human, Gorilla, Orangutan (100%), Chimpanzee, Gibbon, Galago, Bovine, Horse (92%), Monkey, Marmoset, Panda, Dog, Rabbit (83%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (5 μg/mL), Peptide-ELISA (1:128000)

Usage: Peptide ELISA: antibody detection limit dilution 1:128000. Western blot: Preliminary experiments gave bands at approx 75kD and 37kD in Human Cerebellum lysates after 0.3 μg/mL antibody staining. Please note that currently we cannot find an explanation in the literature for the bands we observe given the calculated size of 51.0kD according to NP_000802.2. Both detected bands were successfully blocked by incubation with the immunizing peptide (and BLAST results with the immunizing peptide sequence did not identify any other proteins to explain the additional bands).

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for GABRA6

Target: GABRA6 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 6 (GABRA6))

Alternative Name: GABRA6 (GABRA6 Products)

Synonyms: LOC100224835 antibody, GABRA6 antibody, Gabra-6 antibody, alpha6 antibody, si:dkey-217k23.1 antibody, zgc:73148 antibody, gamma-aminobutyric acid type A receptor alpha 6 subunit antibody, gamma-aminobutyric acid type A receptor alpha6 subunit antibody, gamma-aminobutyric acid (GABA) A receptor, subunit alpha 6 antibody, gamma-aminobutyric acid (GABA) A receptor, alpha 6a antibody, Gabra6 antibody, GABRA6 antibody, gabra6a antibody

Background: Name/Gene ID: GABRA6
Subfamily: GABA A receptor
Family: Ion Channel

Synonyms: GABRA6, GABA A receptor alpha 6, GABA(A) receptor, alpha 6

Gene ID: 2559

NCBI Accession: NP_000802

Pathways: Synaptic Membrane