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MLX Interacting Protein-Like (MLXIPL) antibody
| Antigen | MLX Interacting Protein-Like (MLXIPL) |
| Synonyms | ChREBP, WS-bHLH, Wbscr14, bHLHd14, MLXIPL |
| Clonality | Polyclonal |
| Host |
 Alternatives Rabbit |
| Reactivity |
Alternatives Human, Mouse (Murine), Rat (Rattus) |
| Conjugate |
Alternatives Un-conjugated |
| Application |
Alternatives Chromatin Immunoprecipitation (ChIP), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB) |
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4 references available |
| Catalog no. | ABIN189747 |
| Quantity | 25 µL (1.1 mg/ml) (Variants) |
| Price | Product not available in this region. |
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Additional Information
| Alternative name | MLXIPL |
| Gene ID | 51085 |
| Immunogen | An C-terminal synthetic peptide made to the human ChREBP protein sequence(between residues 800-852). |
| Cross-Reactivity | Human, Rat (Rattus) |
| Description | ChREBP is a transcription factor involved in activating genes that encode enzymes offatty acid biosynthesis in liver and adipose. This protein may have relevance to lipidmetabolism, obesity, and type II diabetes. Alternate Names: anti-WBSCR14 antibody, anti-Williams Beuren Syndrome Chromosome Region 14antibody, anti-MIO antibody, anti-MONDOB antibody, anti-WS-bHLH antibody. Related Diseases: Williams-Beuren syndrome, Cancer |
| Specificity | This antibody is specific for ChREBP. Species Reactivity: This antibody reacts with human, mouse (see Dentin et al) and rat ChREBP. There is83% homology of the immunogen with the mouse ChREBP protein. Other species havenot been tested. Localization: Nuclear. |
Application Details
| Application Notes | Suggested working dilutions: chromatin immunofluorescence 1:100-1:500,Western Blot 1/200 |
| Concentration | 1.1 mg/ml |
| Purification | Purified |
| Buffer | Preservative: 0.1% sodium azide. |
| Storage | Store at 4C. Do not freeze. |
| Restrictions | For Research Use only |
Publications
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Xu, Christian, Jump: "Regulation of rat hepatic L-pyruvate kinase promoter composition and activity by glucose, n-3 polyunsaturated fatty acids, and peroxisome proliferator-activated receptor-alpha agonist." in: The Journal of biological chemistry, Vol. 281, Issue 27, pp. 18351-62, 2006 (PubMed).
Wang, Botolin, Xu et al.: "Regulation of hepatic fatty acid elongase and desaturase expression in diabetes and obesity." in: Journal of lipid research, Vol. 47, Issue 9, pp. 2028-41, 2006 (PubMed). Dentin, Benhamed, Hainault et al.: "Liver-specific inhibition of ChREBP improves hepatic steatosis and insulin resistance in ob/ob mice." in: Diabetes, Vol. 55, Issue 8, pp. 2159-70, 2006 (PubMed). Erhuma, Salter, Sculley et al.: "Prenatal exposure to a low-protein diet programs disordered regulation of lipid metabolism in the aging rat." in: American journal of physiology. Endocrinology and metabolism, Vol. 292, Issue 6, pp. E1702-14, 2007 (PubMed). |
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Alternatives
Alternatives for antigen "MLX Interacting Protein-Like (MLXIPL)", type "Antibodies"
| Hosts | Rabbit (36) |
| Reactivities | Human (36), Mouse (Murine) (24), Rat (Rattus) (24), Cow (Bovine) (20), Chicken (19), Dog (Canine) (19), Horse (Equine) (18), Pig (Porcine) (18), Cat (Feline) (1) |
| Applications | Immunofluorescence (IF) (21), Western Blotting (WB) (19), ELISA (12), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (8), Immunohistochemistry (IHC) (5), Immunoprecipitation (IP) (5), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Chromatin Immunoprecipitation (ChiP) (1), Immunoelectron Microscopy (IEM) (1) |
| Conjugates | Biotin (2), HRP (2), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1) |
| Epitopes | C-Term (4), C-Term,AA 623-653 (1), Internal Region (1), Isoform 1 alpha,C-Term (1), N-Term (1) |
