Uncoupling Protein 2 (Mitochondrial, Proton Carrier) (UCP2) antibody

Antigen: Uncoupling Protein 2 (Mitochondrial, Proton Carrier) (UCP2)

Synonyms: UCPH, BMIQ4, SLC25A8, Slc25a8, UCP2, DKFZp470P1633, ucp2, MGC53319, MGC75881, cb74, MGC65762, MGC76853, K19M22.21, K19M22_21, UNCOUPLING PROTEIN 2

Clonality: Polyclonal

Host: Goat

Reactivity: Human

Application: ELISA, Western Blotting (WB)

Catalog no.: ABIN190824

Additional Information

Alternative name: Uncoupling protein 2 / UCP2

Gene ID: 7351, 22228 (mouse), 54315 (rat)

Immunogen: Peptide with sequence C-DSVKQFYTKGSEH, from the internal region of the protein sequence according to NP_003346.2

Format: Affinity-purified

Description: All names and symbols: UCP2, uncoupling protein 2 (mitochondrial, proton carrier), SLC25A8, UCPH , uncoupling protein 2, uncoupling protein-2. Official Symbol: UCP2. RefSeq number(s): NP_003346.2.

Specificity: Expected from sequence similarity: Human, Mouse, Rat, Dog

Application Details

Application Notes: Peptide ELISA: antibody detection limit dilution 1:4000. Western Blot: Approx 35kDa band observed in Human Liver lysates (calculated MW of 33.2kDa according to NP_003346.2). Recommended concentration: 0.2-1µg/ml..

Concentration: 100µg specific antibody in 200µl

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Buffer: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Storage: For long-term storage keep aliquots at -20°C. (Store no longer than 12 months at 4°C). Minimize freezing and thawing.

Restrictions: For Research Use only

Publications

Publications: De Souza, Araujo, Stoppiglia et al.: "Inhibition of UCP2 expression reverses diet-induced diabetes mellitus by effects on both insulin secretion and action." in: The FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 21, Issue 4, pp. 1153-63, 2007 (PubMed).