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Details for Product No. ABIN190858

Transmembrane Emp24-Like Trafficking Protein 10 (Yeast) (TMED10) (C-Term) antibody

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Antigen
Synonyms P24(DELTA), S31I125, S31III125, TMP21, Tmp-21-I, p23, 1110014C03Rik, Tmp21, p24delta1, fe06g04, wu:fb98e10, wu:fe06g04, zgc:85681, tmp21
Epitope
»Alternatives C-Term
Reactivity
»Alternatives Human, Mouse (Murine), Rat (Rattus), Dog (Canine)
Host
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Methode Type Peptide ELISA
Application
»Alternatives ELISA, Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN190858
Quantity 100 µg
Price
261.61 $   Plus shipping costs $45.00
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Availability Ships within 5 Business Days
Immunogen Peptide with sequence C-YLRRFFKAKKLIE, from the C Terminus of the protein sequence according to NP_006818.3.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name TMP21 / TMED10
Background Synonyms: TMED10, transmembrane emp24-like trafficking protein 10 (yeast), P24(DELTA), S31I125, S31III125, TMP21, Tmp-21-I, 21 kDa transmembrane trafficking protein, transmembrane emp24 domain-containing protein 10
Gene ID 10972, 68581, 84599
NCBI Accession NP_006818.3
Application Notes ELISA: antibody detection limit dilution 1:1000.
Western blot: Preliminary experiments gave an approx 75 kDa band in Human and Rat Pancreas lysates after 1 µg/mL antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 25.0 kDa according to NP_006818.3. The 75 kDa band was successfully blocked by incubation with the immunizing peptide.
Restrictions For Research Use only
Format Liquid
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
Chen, Hasegawa, Schmitt-Ulms et al.: "TMP21 is a presenilin complex component that modulates gamma-secretase but not epsilon-secretase activity." in: Nature, Vol. 440, Issue 7088, pp. 1208-12, 2006 (PubMed).

Alternatives for antigen "Transmembrane Emp24-Like Trafficking Protein 10 (Yeast) (TMED10)", type "Antibodies"
Hosts (60), (4)
Reactivities (58), (47), (46), (23), (15), (14), (12), (10), (6), (1)
Applications (51), (27), (22), (16), (10), (2), (2), (1), (1)
Conjugates (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (13), (6), (5), (2), (1), (1), (1), (1)
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