Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 3 (KCNC3) antibody

Antigen: Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 3 (KCNC3)

Synonyms: KV3.3, SCA13, KSHIIID, KCNC3, kcnc3-A, Kv3.1, kcnc1, kv3.3, sca13, kshiiid, MGC84730

Clonality: Polyclonal

Host: Goat

Reactivity: Human

Application: ELISA, Western Blotting (WB)

Catalog no.: ABIN190903

Additional Information

Alternative name: KCNC3

Gene ID: 3748

Immunogen: C-KPGPPSFLPDLNAN

Format: Affinity-purified

Description: All names and symbols: KCNC3, potassium voltage-gated channel, Shaw-related subfamily, member 3, KSHIIID, KV3.3, SCA13 , Shaw-related voltage-gated potassium channel protein 3, spinocerebellar ataxia 13, voltage-gated potassium channel protein KV3.3. Official Symbol: KCNC3. RefSeq number(s): NP_004968.2

Specificity: Human

Application Details

Application Notes: Peptide ELISA: antibody detection limit dilution 1:32,000. Western Blot: Approx 80Da band observed in human brain (Frontal Cortex) lysates (calculated MW of 80.6kDa according to NP_004968.2). Recommended concentration: 0.3-1µg/ml.

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Storage: Aliquot and store at -20°C. Minimize freezing and thawing.

Research Area: Neurology

Restrictions: For Research Use only

Images

ABIN190903 (0.3µg/ml) staining of human brain (Frontal Cortex) lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Publications

Publications: Waters, Minassian, Stevanin et al.: "Mutations in voltage-gated potassium channel KCNC3 cause degenerative and developmental central nervous system phenotypes." in: Nature genetics, Vol. 38, Issue 4, pp. 447-51, 2006 (PubMed).