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DISC1 antibody (Disrupted in Schizophrenia 1) (Internal Region)

Details for Product anti-DISC1 Antibody No. ABIN190904, Supplier: Log in to see
Antigen
  • DISC1
  • C1orf136
  • SCZD9
  • disrupted in schizophrenia 1
  • disc1
  • DISC1
  • Disc1
Epitope
Internal Region
49
46
19
18
17
14
9
5
5
5
4
2
2
2
2
1
1
1
1
1
1
Reactivity
Human
158
79
51
1
Host
Goat
159
15
15
3
Clonality
Polyclonal
Conjugate
This DISC1 antibody is un-conjugated
9
8
7
4
4
3
3
3
3
3
3
2
2
2
1
1
1
1
1
1
1
Methode Type
Peptide ELISA
Application
ELISA, Western Blotting (WB)
144
76
64
57
30
26
25
15
12
7
3
3
1
Options
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Immunogen Peptide with sequence C-HSEDKRKTPLKVLE, from the internal region of the protein sequence according to NP_001012975.1, NP_061132.2.
Blocking Peptide Blocking peptide for this product available: ABIN369206
Specificity This antibody is expected to recognise isoforms L ( NP_061132.2) and Lv (NP_001012975.1) only.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name DISC1 (DISC1 Antibody Abstract)
Background Synonyms: DISC1, disrupted in schizophrenia 1, RP4-730B13.1, KIAA0457
Gene ID 27185
NCBI Accession NP_061132, NP_001012975
Research Area Neurology, Alzheimer's Disease
Application Notes ELISA: antibody detection limit dilution 1:128000.
Western blot: Approx 100 kDa band observed in human brain (cerebellum, hippocampus and frontal cortex) lysates (calculated MW of 93.6 kDa according to NP_001012975.1). Recommended concentration: 0.1-0.3 µg/mL.
Restrictions For Research Use only
Format Liquid
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
Supplier Images
 image for anti-DISC1 antibody (Disrupted in Schizophrenia 1) (Internal Region) (ABIN190904) ABIN190904 (0.1µg/ml) staining of human brain (hippocampus) lysate (35µg protein in R...
Background publications Millar, Pickard, Mackie, James, Christie, Buchanan, Malloy, Chubb, Huston, Baillie, Thomson, Hill, Brandon, Rain, Camargo, Whiting, Houslay, Blackwood, Muir, Porteous: "DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling." in: Science (New York, N.Y.), Vol. 310, Issue 5751, pp. 1187-91, 2005 (PubMed).