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Disrupted in Schizophrenia 1 (DISC1) (Internal Region) antibody

Details for Product No. ABIN190904, Supplier: Log in to see
Antigen
  • DISC1
  • C1orf136
  • SCZD9
Epitope
Internal Region
56
21
20
14
6
5
5
5
5
4
4
2
2
2
1
1
1
1
1
1
Reactivity
Human
143
46
23
Host
Goat
131
14
14
3
Clonality
Polyclonal
Conjugate
Un-conjugated
7
6
5
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Methode Type
Peptide ELISA
Application
ELISA, Western Blotting (WB)
130
73
55
31
14
13
7
7
3
3
1
Supplier
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Immunogen Peptide with sequence C-HSEDKRKTPLKVLE, from the internal region of the protein sequence according to NP_001012975.1, NP_061132.2.
Blocking Peptide Blocking peptide for this product available: ABIN369206
Specificity This antibody is expected to recognise isoforms L ( NP_061132.2) and Lv (NP_001012975.1) only.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name DISC1 (DISC1 Antibody Abstract)
Background Synonyms: DISC1, disrupted in schizophrenia 1, RP4-730B13.1, KIAA0457
Gene ID 27185
NCBI Accession NP_061132, NP_001012975
Research Area Neurology, Alzheimer's Disease
Pathways
Application Notes ELISA: antibody detection limit dilution 1:128000.
Western blot: Approx 100 kDa band observed in human brain (cerebellum, hippocampus and frontal cortex) lysates (calculated MW of 93.6 kDa according to NP_001012975.1). Recommended concentration: 0.1-0.3 µg/mL.
Restrictions For Research Use only
Format Liquid
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
Supplier Images
 image for anti-Disrupted in Schizophrenia 1 (DISC1) (Internal Region) antibody (ABIN190904) ABIN190904 (0.1µg/ml) staining of human brain (hippocampus) lysate (35µg protein in R...
Background publications Millar, Pickard, Mackie et al.: "DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling." in: Science (New York, N.Y.), Vol. 310, Issue 5751, pp. 1187-91, 2005 (PubMed).