Natriuretic Peptide Receptor A/guanylate Cyclase A (Atrionatriuretic Peptide Receptor A) (NPR1) (AA 294-308) antibody

Antigen: Natriuretic Peptide Receptor A/guanylate Cyclase A (Atrionatriuretic Peptide Receptor A) (NPR1)

Synonyms: ANPa, NPRA, ANPRA, GUC2A, GUCY2A, Gca, Npra, Anpra, NPR-A

Epitope: AA 294-308

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB), Immunofluorescence (IF)

Catalog no.: ABIN191701

Additional Information

Characteristics: Synonyms: ANP receptor A, ANP-A, NPR-A, Guanylate cyclase, GC-A, Atrial natriuretic peptide A-typereceptor

Alternative name: NPR1 / ANPRA

Swiss-Prot: P16066

Immunogen: Synthetic human NPR-A (aa 294-308) KLH conjugatedAA Sequence: LKQLKHLAYEQFNFT

Cross-Reactivity: Human

Description: Natriuretic peptide receptor A is a receptor for atrial natriuretic peptide, and has guanylatecyclase activity on binding of ANF. There seem to be at least three ANP receptors: two withguanylate cyclase activity(ANP-A and ANP-B) and one (ANP-C) which is probablyresponsible for the clearance of ANP from the circulation without a role in signaltransduction. ANP-A Belongs to the adenylyl cyclase class-4/guanylyl cyclase family andcontains 1 protein kinase-like domain.

Specificity: This antibody detects Natriuretic Peptide Receptor A (aa 294-308). Species: Human. Others not tested. Add. Information: LocusID 4881

Application Details

Application Notes: Western blot (1: 5000). Immunohistochemistry on paraffin sections (1: 4000). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Purification: Serum

Storage: Store lyophilized at 2 - 8 °C and reconstituted at -20 °C. Avoid repeated freezing andthawing. Shelf life: One year from despatch.

Restrictions: For Research Use only