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Epidermal Growth Factor Receptor (EGFR) antibody

Antigen

Epidermal Growth Factor Receptor (EGFR)
Synonyms
ERBB, HER1, mENA, ERBB1, PIG61, Wa5, wa2, Erbb, Errp, wa-2, AI552599, 9030024J15Rik, ErbB-1, C-erb, D-EGFR, D-Egf, DEGFR, DER, DER flb, DER/EGFR, DER/faint little ball, DER/top, DER/torpedo, DmHD-33,  ... show more
Clonality Polyclonal
Host
Alternatives

Rabbit
Reactivity
Alternatives

Human
Application
Alternatives Enzyme Immunoassay (EIA), Western Blotting (WB), Immunofluorescence (IF)
Catalog no. ABIN191749
Quantity 20 µl  (Variants)
Price 195.00 $   Plus shipping costs $35.00
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Availability Ships within 7 to 10 Business Days

Additional Information
Application Details Alternatives Secondary Antibodies Variants back to top

Characteristics Synonyms: Epidermal growth factor receptor, EGF Receptor, erbB-1, c-ErbB-1, Receptor tyrosine-proteinkinase erbB-1, Proto-oncogene c-ErbB-1
Alternative name EGFR / ERBB1
Swiss-Prot P00533
Immunogen Human native EGF-Receptor
Cross-Reactivity Human
Description Protein kinases are enzymes that transfer a phosphate group from a phosphate donor ontoan acceptor amino acid in a substrate protein. By this basic mechanism, protein kinasesmediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism,transcription, cell cycle progression, cytoskeletal rearrangement and cell movement,apoptosis, and differentiation. The protein kinase family is one of the largest families ofproteins in eukaryotes, classified in 8 major groups based on sequence comparison oftheir tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. Epidermal Growthfactor receptor (EGFR) is the prototype member of the type 1 receptor tyrosine kinases. EGFR overexpression in tumors indicates poor prognosis and is observed in tumors of thehead and neck, brain, bladder, stomach, breast, lung, endometrium, cervix, vulva, ovary,esophagus, stomach and in squamous cell carcinoma.
Specificity This antibody detects EGF-Receptor. Species: Human. Others not tested. Add. Information: LocusID 1956
Synonyms ERBB, HER1, mENA, ERBB1, PIG61, Wa5, wa2, Erbb, Errp, wa-2, AI552599, 9030024J15Rik, ErbB-1, C-erb, D-EGFR, D-Egf, DEGFR, DER, DER flb, DER/EGFR, DER/faint little ball, DER/top, DER/torpedo, DmHD-33, EFG-R, EGF-R, EGFR, EK2-6, Egf, El, Elp, Elp-1, Elp-B1, Elp-B1RB1, HD-33, Torpedo/DER, Torpedo/Egfr, c-erbB, d-egf-r, dEGFR1, flb, l(2)05351, l(2)09261, l(2)57DEFa, l(2)57EFa, l(2)57Ea, pnt, top, top/DER, top/flb, DmelCG10079, CG10079, egfr, EGFR12, EGFR15, egfr1, Erbb2

Application Details
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Application Notes ELISA (1: 10.000). Immunflourescence (1: 1.000). Western blot (1: 500). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Purification Serum
Storage Store lyophilized at 2 - 8 °C and reconstituted at -20 °C. Avoid repeated freezing andthawing. Shelf life: One year from despatch.
Restrictions For Research Use only

Alternatives
Application Details Secondary Antibodies Variants back to top

Alternatives for antigen "Epidermal Growth Factor Receptor (EGFR)", type "Antibodies"
Hosts Rabbit (417), Mouse (167), Rat (8), Sheep (7), Goat (2)
Reactivities Human (580), Mouse (Murine) (251), Rat (Rattus) (227), Dog (Canine) (33), Rabbit (18), Pig (Porcine) (17), Cow (Bovine) (6), Chicken (5), Horse (Equine) (2), Sheep (Ovine) (2)
Applications Western Blotting (WB) (417), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (134), Immunoprecipitation (IP) (120), Enzyme Immunoassay (EIA) (112), Immunohistochemistry (IHC) (103), Immunofluorescence (IF) (98), ELISA (92), Flow Cytometry (FACS) (90), Immunohistochemistry (Frozen Sections) (IHC (fro)) (43), Dot Blot (Dot) (28), Blocking Antibody (Inhibition) (16), Immunocytochemistry (ICC) (10), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (4), Functional Studies (Func) (3), ELISA (Detection) (2), Immunoelectron Microscopy (IEM) (2), Neutralization (Neut) (2), Blocking Antibody (Inhibition) (1)
Conjugates Biotin (35), FITC (5), Alexa Fluor 488 (3), PE (3), Alexa Flour 488 (2), Alexa Fluor 350 (2), Alexa Fluor 555 (2), Alexa Fluor 647 (2), Cy3 (2), Cy5 (2), Cy5.5 (2), Cy7 (2), Gold (2), HRP (2), PE,Cy3 (2), PE,Cy5 (2), PE,Cy5.5 (2), PE,Cy7 (2), RBITC (2)
Epitopes pTyr1197 (19), C-Term (16), pTyr869 (15), pTyr1092 (14), pTyr1172 (13), pThr678 (12), pTyr1110 (12), pSer1070 (11), pThr693 (10), N-Term (5), pTyr1016 (4), pTyr1069 (4), AA 1-203 (2), AA 1140-1160 (2), AA 960-980 (2), Extracell. non Ligand binding Site (2), S695 (2), Y1125 (2), Y869 (2), Y998 (2), pSer1026 (2), pSer1071 (2), pSer1166 (2), pSer1190 (2), pSer695 (2), pSer768 (2), pTyr1125 (2), pTyr1173 (2), pTyr998 (2), AA 1189-1199 (1), AA 985-996 (1), Ab-1016 (1), Ab-1026 (1), Ab-1069 (1), Ab-1071 (1), Amino Acids 1165-1186 (1), External Domain (1), Extracellular non-ligand binding site (1), S1026 (1), S1070 (1), S1071 (1), S1166 (1), S1190 (1), S991 (1), T678 (1), TYR1173 (1), Y1016 (1), Y1069 (1), Y1092 (1), Y1110 (1), Y1172 (1), Y978 (1), extracellular ligand binding site (1), internal (1), pS1070 (1), pS768 (1), pSer1142 (1), pSer967 (1), pTyr1101 (1), pTyr1173, pTyr1248 (1), pTyr992 (1), pY1016 (1), pY1092 (1), pY1172 (1), prylated At Threonine 654 (1), prylated At Tyrosine 1045 (1), prylated At Tyrosine 1173 (1), prylated At Tyrosine 845 (1), prylated at Serine 1047 (1)

Variants
Application Details Alternatives Secondary Antibodies back to top

Variants