Insulin (INS) antibody
| Antigen |
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| Synonyms |
ILPR, IRDN, INS, MGC159719, ins1, xins, ins1-a, Insulin |
| Clonality |
Polyclonal |
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Host
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Reactivity
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Human (183), Pig (Porcine) (91), Rat (Rattus) (58), Mouse (Murine) (45), Cow (Bovine) (44), Rabbit (29), Horse (Equine) (22), Dog (Canine) (9), Chicken (3), Guinea Pig (3), Sheep (Ovine) (3), Cat (Feline) (2)
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Application
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 Alternatives Enzyme Immunoassay (EIA), Radioimmunoassay (RIA)
Immunofluorescence (IF) (77), Flow Cytometry (FACS) (71), Enzyme Immunoassay (EIA) (58), ELISA (51), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (41), Radioimmunoassay (RIA) (27), Immunohistochemistry (Frozen Sections) (IHC (fro)) (26), Western Blotting (WB) (26), Immunohistochemistry (IHC) (17), Immunoprecipitation (IP) (14), ELISA (Capture) (6), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (6), Functional Studies (Func) (4), Immunocytochemistry (ICC) (4), Immunoelectron Microscopy (IEM) (3)
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| Catalog no. |
ABIN191882 |
| Quantity |
20 µl (Variants) |
| Price |
265.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 7 to 10 Business Days |
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Characteristics
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Synonyms: INS
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Alternative name
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Insulin
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Swiss-Prot
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P01308
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Immunogen
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Bovine Insulin.
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Cross-Reactivity
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Cow (Bovine)
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Description
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Insulin is one of the major regulatory hormones of intermediate metabolism throughoutthe body. The biological actions of this hormone involve integration of carbohydrate,protein, and lipid metabolism. Insulin enhances membrane transport of glucose, aminoacids, and certain ions. It also promotes glycogen storage, formation of triglycerides andsynthesis of proteins and nucleic acids. Immunocytochemical investigations havelocalized insulin in the B cells of pancreatic islets of Langerhans. Deficiency of insulinresults in diabetes mellitus, one of the leading causes of morbidity and mortality in thegeneral population. Insulin is also present in tumors of B cell origin such as insulinoma.
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Specificity
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This antibody detects Insulin. No cross reaction with IGF-1, IGF-2, Glucagon and C-Peptide. Species: Bovine, deers, domestic ruminants. Others not tested.
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Application Notes
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RIA. EIA. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Purification
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Serum
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Storage
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Store lyophilized at 2-8°C and reconstituted at -20°C. Avoid repeated freezing and thawing. Shelf life: One year from despatch.
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Research Area
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Neurology, Diabetes, Hormones
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Restrictions
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For Research Use only
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Alternatives for antigen "Insulin (INS)", type "Antibodies"
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Hosts
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Mouse (104), Rabbit (96), Guinea Pig (7), Sheep (4), Chicken (1)
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Reactivities
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Human (183), Pig (Porcine) (91), Rat (Rattus) (58), Mouse (Murine) (45), Cow (Bovine) (44), Rabbit (29), Horse (Equine) (22), Dog (Canine) (9), Chicken (3), Guinea Pig (3), Sheep (Ovine) (3), Cat (Feline) (2)
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Applications
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Immunofluorescence (IF) (77), Flow Cytometry (FACS) (71), Enzyme Immunoassay (EIA) (58), ELISA (51), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (41), Radioimmunoassay (RIA) (27), Immunohistochemistry (Frozen Sections) (IHC (fro)) (26), Western Blotting (WB) (26), Immunohistochemistry (IHC) (17), Immunoprecipitation (IP) (14), ELISA (Capture) (6), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (6), Functional Studies (Func) (4), Immunocytochemistry (ICC) (4), Immunoelectron Microscopy (IEM) (3)
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Conjugates
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Alexa Fluor 350 (6), Alexa Fluor 488 (6), Alexa Fluor 555 (6), Alexa Fluor 647 (6), Biotin (6), PE,Cy5.5 (6), HRP (5), FITC (4), Alexa Flour 488 (3), Cy3 (3), Cy5 (3), Cy5.5 (3), Cy7 (3), Gold (3), PE (3), PE,Cy3 (3), PE,Cy5 (3), PE,Cy7 (3), RBITC (3)
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Epitopes
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beta chain (3), AA 57-87 (2), C-Term (2), Center (1)
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