DEFB103A antibody (AA 6-22)

Catalog No. ABIN192003

Product Details anti-DEFB103A Antibody

Target: DEFB103A (Defensin, beta 103A (DEFB103A))

Binding Specificity: AA 6-22

Reactivity: Human, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This DEFB103A antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Radioimmunoassay (RIA)

Specificity: This antibody detects Human beta-Defensin 3 (aa 6-22), Rat beta-Defensin 3.

Characteristics: Synonyms: DEFB103A, DEFB103B, BD3, DEFB3, HBP3, HBD3, DEFB103, Beta-defensin 103, Defensin-likeprotein, Defensin beta 103

Purification: Protein G Chromatography

Immunogen: Synthetic Human beta-Defensin 3 (aa 6-22)Genename: DEFB103A and DEFB103BAA Sequence: LQKYYCRVRGGRCAVLS

Clone: L3-18b-E1

Isotype: IgG1

Application Details

Application Notes: RIA. ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore in aqua bidest to 1 mg/mL.

Buffer: 50 mM TRIS pH 7.4

Storage: 4 °C/-20 °C

Storage Comment: Store lyophilized at 2-8 °C and reconstituted at -20 °C. Avoid repeated freezing and thawing.
Shelf life: One year from despatch.

Expiry Date: 12 months

Target Details for DEFB103A

Target: DEFB103A (Defensin, beta 103A (DEFB103A))

Alternative Name: Defensin beta 3 (DEFB103A Products)

Synonyms: BD-3 antibody, DEFB-3 antibody, DEFB103 antibody, DEFB3 antibody, HBD3 antibody, HBP-3 antibody, HBP3 antibody, hBD-3 antibody, DEFB103B antibody, defensin beta 103A antibody, defensin beta 103B antibody, defensin, beta 103A antibody, beta-defensin 103 antibody, DEFB103A antibody, DEFB103B antibody, LOC694235 antibody, LOC100359096 antibody

Background: Beta Defensin 3 exhibits antimicrobial activity against Gram positive bacteria S.aureus and S.pyogenes, Gram negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. It kills multiresistant S.aureus and vancomycin resistant E.faecium, but it appears to have no significant hemolytic activity. Beta Defensin 3 is highly expressed in skin and tonsils, and to a lesser extent in trachea, uterus, kidney, thymus, adenoid, pharynx and tongue. Low expression is observed in salivary gland, bone marrow, colon, stomach, polyp and larynx, with no expression in small intestine. Expression is induced by infection of bacteria and by interferon gamma. Beta Defensin 3 belongs to the beta defensin family.Synonyms: BD3, Beta-defensin 103, DEFB103, DEFB103A, DEFB103B, DEFB3, Defensin beta 103, Defensin-like protein, HBD3, HBP3

Gene ID: 414325

UniProt: P81534

Pathways: Production of Molecular Mediator of Immune Response