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Details for Product No. ABIN192401

HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG) (AA 61-83) antibody

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Antigen
Synonyms MHC-G, B-F, B-F-S04, B-F-S05, B-F-S06, B-F-S07, B-FI, B-FIV, BF2, BFa2, BFw-03, BFw-05, BFz-01
Epitope
»Alternatives AA 61-83
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), ELISA
Pubmed 13 references available
Catalog no. ABIN192401
Quantity 0.1 mg
Price
377.52 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 4 to 5 Business Days
Immunogen amino acids 61-83 of HLA-G of human origin
Clone 4H84
Isotype IgG1
Specificity The antibody 4H84 recognizes HLA-G molecule (39 kDa). HLA-G belongs to the MHC ClassI molecules (MHC Class Ib, nonclassical) and it is expressed on the surface of trophoblastcells.
Purification Purified from ascites by protein-A affinity chromatography.
Purity > 95% (by SDS-PAGE)
Alternative Name HLA-G
Research Area Major Histocompatibility Complex (MHC)
Application Notes Immunohistochemistry (paraffin sections) - ImmunocytochemistryELISA. Application note: The antibody 4H84 has been tested as the capture antibody in a sandwichELISA for analysis of heavy chains of all HLA-G isoforms in combination with antibodyMEM-G/1 (cat. no. 1B-291-C100).
Restrictions For Research Use only
Concentration 1 mg/ml
Buffer Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Preservative Sodium azide
Storage 4 °C
Storage Comment Do not freeze. Do not use after expiration date stamped on vial label.
Product cited in: Guo, Chen, Ruan et al.: "HLA-G expression is irrelevant to prognosis in patients with acute myeloid leukemia." in: Leukemia research, 2011 (PubMed). (1:1000).

Paul, Rouas-Freiss, Khalil-Daher et al.: "HLA-G expression in melanoma: a way for tumor cells to escape from immunosurveillance." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 8, pp. 4510-5, 1998 (PubMed).

Urosevic, Kurrer, Kamarashev et al.: "Human leukocyte antigen G up-regulation in lung cancer associates with high-grade histology, human leukocyte antigen class I loss and interleukin-10 production." in: The American journal of pathology, Vol. 159, Issue 3, pp. 817-24, 2001 (PubMed).

Blaschitz, Hutter, Dohr: "HLA Class I protein expression in the human placenta." in: Early pregnancy (Online), Vol. 5, Issue 1, pp. 67-9, 2001 (PubMed).

Menier, Saez, Horejsi et al.: "Characterization of monoclonal antibodies recognizing HLA-G or HLA-E: new tools to analyze the expression of nonclassical HLA class I molecules." in: Human immunology, Vol. 64, Issue 3, pp. 315-26, 2003 (PubMed).

Poláková, Krcová, Kuba et al.: "Analysis of HLA-G expression in malignant hematopoetic cells from leukemia patients." in: Leukemia research, Vol. 27, Issue 7, pp. 643-8, 2003 (PubMed).

Poláková, Kuba, Russ: "The 4H84 monoclonal antibody detecting beta2m free nonclassical HLA-G molecules also binds to free heavy chains of classical HLA class I antigens present on activated lymphocytes." in: Human immunology, Vol. 65, Issue 2, pp. 157-62, 2004 (PubMed).

Gonen-Gross, Achdout, Arnon et al.: "The CD85J/leukocyte inhibitory receptor-1 distinguishes between conformed and beta 2-microglobulin-free HLA-G molecules." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 175, Issue 8, pp. 4866-74, 2005 (PubMed).

Juch, Blaschitz, Daxböck et al.: "A novel sandwich ELISA for alpha1 domain based detection of soluble HLA-G heavy chains." in: Journal of immunological methods, Vol. 307, Issue 1-2, pp. 96-106, 2005 (PubMed).

Barrier, Kendall, Sharpe-Timms et al.: "Characterization of human leukocyte antigen-G (HLA-G) expression in endometrial adenocarcinoma." in: Gynecologic oncology, Vol. 103, Issue 1, pp. 25-30, 2006 (PubMed).

Gonen-Gross, Goldman-Wohl, Huppertz et al.: "Inhibitory NK receptor recognition of HLA-G: regulation by contact residues and by cell specific expression at the fetal-maternal interface." in: PLoS ONE, Vol. 5, Issue 1, pp. e8941, 2010 (PubMed).

Gan, Huang, Zhang et al.: "Tumor-specific upregulation of human leukocyte antigen-G expression in bladder transitional cell carcinoma." in: Human immunology, 2010 (PubMed).

Zheng, Wang, Zhang et al.: "Up-regulation of HLA-G expression in cervical premalignant and malignant lesions." in: Tissue antigens, Vol. 77, Issue 3, pp. 218-24, 2011 (PubMed).

Alternatives for antigen "HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG)", type "Antibodies"
Hosts (205), (69), (1)
Reactivities (270), (4), (1), (1)
Applications (174), (107), (98), (56), (56), (54), (37), (30), (18), (14), (12), (7), (2), (1), (1)
Conjugates (30), (29), (22), (8), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (1), (1)
Epitopes (15), (7), (5), (2), (2), (1), (1)
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