F2RL3 antibody

Catalog No. ABIN1944933

Product Details anti-F2RL3 Antibody

Target: F2RL3 (Coagulation Factor II (Thrombin) Receptor-Like 3 (F2RL3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This F2RL3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Isotype: IgG

Application Details

Application Notes: IF: 1:100. WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Storage: 4 °C,-20 °C

References for anti-F2RL3 antibody (ABIN1944933)

Kahn, Nakanishi-Matsui, Shapiro, Ishihara, Coughlin: "Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin." in: The Journal of clinical investigation, Vol. 103, Issue 6, pp. 879-87, (1999) (PubMed).

Kahn, Hammes, Botka, Coughlin: "Gene and locus structure and chromosomal localization of the protease-activated receptor gene family." in: The Journal of biological chemistry, Vol. 273, Issue 36, pp. 23290-6, (1998) (PubMed).

Xu, Andersen, Whitmore, Presnell, Yee, Ching, Gilbert, Davie, Foster: "Cloning and characterization of human protease-activated receptor 4." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 12, pp. 6642-6, (1998) (PubMed).

Kahn, Zheng, Huang, Bigornia, Zeng, Moff, Farese, Tam, Coughlin: "A dual thrombin receptor system for platelet activation." in: Nature, Vol. 394, Issue 6694, pp. 690-4, (1998) (PubMed).

Target Details for F2RL3

Target: F2RL3 (Coagulation Factor II (Thrombin) Receptor-Like 3 (F2RL3))

Alternative Name: PAR4 (F2RL3 Products)

Synonyms: F2RL3 antibody, PAR4 antibody, F2R like thrombin or trypsin receptor 3 antibody, F2R like thrombin/trypsin receptor 3 antibody, coagulation factor II (thrombin) receptor-like 3 antibody, F2RL3 antibody, F2rl3 antibody

Background: Receptor for activated thrombin or trypsin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation.

Molecular Weight: 41133 Da

Gene ID: 9002

UniProt: Q96RI0

Pathways: Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process