TXK antibody (AA 515-527)

Catalog No. ABIN1945853

Product Details anti-TXK Antibody

Target: TXK (TXK tyrosine Kinase (TXK))

Binding Specificity: AA 515-527

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This TXK antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Brand: IHC-plus™

Specificity: Human TXK.

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide C-ELLRAVTEIAETW from the C-terminus of human TXK (NP_003319.2). Percent identity with other species by BLAST analysis: Human (100%), Gorilla (92%), Gibbon (92%), Monkey (85%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (5 μg/mL), Peptide-ELISA (1:4000)

Usage: Peptide ELISA: antibody detection limit dilution 1:4000. Western blot: Preliminary experiments gave an approx. 75  kDa band in lysates of cell lines Jurkat and MOLT4 after 1 μg/mL antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 61.3  kDa according to NP_003319.2. The 75  kDa band was successfully blocked by incubation with the immunizing peptide.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for TXK

Target: TXK (TXK tyrosine Kinase (TXK))

Alternative Name: TXK / RLK (TXK Products)

Synonyms: BTKL antibody, PSCTK5 antibody, PTK4 antibody, RLK antibody, TKL antibody, A130089B16Rik antibody, Btkl antibody, Rlk antibody, TXK tyrosine kinase antibody, tyrosine-protein kinase TXK antibody, TXK antibody, Txk antibody, LOC100544958 antibody

Background: Name/Gene ID: TXK
Subfamily: BTK/TEC
Family: Protein Kinase

Synonyms: TXK, PSCTK5, PTK4 protein tyrosine kinase 4, Resting lymphocyte kinase, RLK, TKL, Tyrosine kinase, Tyrosine-protein kinase TXK, Protein-tyrosine kinase 4, BTKL, PTK4, TXK tyrosine kinase

Gene ID: 7294

NCBI Accession: NP_003319

Pathways: Regulation of Leukocyte Mediated Immunity, Hepatitis C