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Product details for BACE1 (Human) Antibody
BACE1 (Human) Antibody
Overview
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| Antigen: | BACE1 |
| Antibody Type: | Polyclonal |
| Application: | Western Blotting (WB), Immunohistochemistry (IHC) |
| Reactivity: | Human, Mouse, Rat |
| Host: | Rabbit |
| Quantity: | |
| Price: | 315,00 € (Plus shipping costs and VAT) |
| Order number: | ABIN195449 |
| Availability: | 10 days until shipment |
Additional Information: BACE1 (Human) Antibody
| Antigen | BACE1 |
| Immunogen | Synthetic peptide of a part of human BACE1 (RLPRETDEEPEEPGRR) |
| Reactivity | Human, Mouse, Rat |
| Antibody Type | Polyclonal |
| Format | Lyophilized |
| Isotype | IgG »Matching secondary antibodies |
| Description | The current understanding of the role of amyloid in Alzheimer's disease (AD) has been established by a remarkable congruence of multiple disciplines: neuropathology, biochemistry, molecular biology, and epidemiological genetics. It is known that amyloid beta is derived, by two sequential cleavages, from the receptor-like amyloid precursor protein (APP). The proteases involved are beta-secretase, identified as the novel aspartyl protease BACE, and gamma-secretase, a multimeric complex containing the presenilins (PS-1, PS-2). BACE1 and BACE2 have been isolated as homologue of BACE, and this antibody reacts to BACE1. (BACE: beta-site APP cleaving enzyme) |
| Host | Rabbit |
| Specificity | Reacts with human, mouse and rat BACE1. |
Application Details: BACE1 (Human) Antibody
| Application | Western Blotting (WB), Immunohistochemistry (IHC) |
| Application Notes | The antibody can be used in immunohistchemistry. The optimal dilution is 1 - 5 ug/mL, however, the dilution rate should be optimized by each laboratories. The antibody can be used for western blotting at 1 - 5 ug/mL. |
| Purification | Purified with antigen peptide |
| Buffer | Lyophilized product from 1% BSA in PBS containing 0.05% NaN3 |
| Storage | Lyophilized product, 5 years at 2 - 8 °C. Solution, 2 years at –20 °C |
| Restrictions | For Research Use only |
External Information: BACE1 (Human) Antibody
| Google Scholar | Find more references for antigen BACE1 on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen BACE1 (Bioinformatic Harvester (EMBL)) |
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