Product details for  RIG-I (R37) (Human) antibody
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RIG-I (R37) (Human) antibody

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Antigen: RIG-I (R37)
Antibody Type: Polyclonal
Application: Western Blotting (WB)
Reactivity: Human, Mouse
Host: Rabbit
Quantity: 100ug
Price: 315,00 €   (Plus shipping costs and VAT)
Order number: ABIN195467
Availability: 10 days until shipment
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Additional Information:  RIG-I (R37) (Human) antibody

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Antigen RIG-I (R37)
Immunogen Synthetic peptide of part of N terminal of human RIG-I (EVQYIQAEKNNKGPMEAAT)
Reactivity Human, Mouse
Antibody Type Polyclonal
Format Affinity purified
Isotype IgG »Matching secondary antibodies
Description Yoneyama et al showed that the DExD/H box-containing RNA helicase retinoic acid inducible gene I (RIG-I), is important in virus-induced activation of type I interferon. RIG-I has an interesting structural feature. it has two copies of a caspase recruitment domain (CARD) at its N terminus in addition to its C-terminal helicase domain. The CARD of RIG-I transduces signals that lead to the activation of IRF-3 and NF-kB. RIG-I functions as an essential regulator for virus-induced antiviral immunity.
Host Rabbit
Specificity Reacts with human and mouse RIG-I

Application Details:  RIG-I (R37) (Human) antibody

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Application Western Blotting (WB)
Application Notes Western blotting in concentration of 1 – 5ug/mL
Purification Purified with antigen peptide
Buffer Lyophilized product from 1% BSA in PBS containing 0.05% NaN3
Storage Lyophilized product, 5 years at 2 – 8 ?. Solution, 2 years at –20 ?. 1.0 mL deionized water will be added to the product (the conc. comes up 100?g/mL)
Research Area Virology, Immunology
Restrictions For Research Use only

Images:  RIG-I (R37) (Human) antibody

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lane 1: HeLa cell lysate without IFN? stimulation. lane 2: HeLa cell lysate with IFN? stimulation. lane 3: L929 cell lysate without IFN? stimulation. lane 4: L929 cell lysate with IFN? stimulation When this antibody is used in Western Blotting, several bands appear although the antibody specifically detects the RIG-I protein. We recommend to perform positive and negative controls in parallel.

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External Information:  RIG-I (R37) (Human) antibody

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Google Scholar Find more references for antigen RIG-I (R37) on Google Scholar™
EMBL Harvester Search human, mouse or rat genome for antigen RIG-I (R37) (Bioinformatic Harvester (EMBL))