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Signal Transducer and Activator of Transcription 5A (STAT5A) (Tyr694) antibody

Details for Product No. ABIN197181
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Antigen
Synonyms MGF, STAT5, AA959963, Stat5, STATA5, STAT5A/MGF, STAT5A
Epitope
Tyr694
(68), (37), (20), (18), (13), (8), (6), (4), (4), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(287), (177), (160), (63), (61), (51), (36), (2)
Host
Rabbit
(263), (39), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(9), (8), (7), (5), (5), (5), (5), (5), (5), (5), (5), (3), (2), (2), (1)
Application
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(237), (112), (112), (81), (50), (26), (21), (15), (11), (11), (6), (5), (2), (2), (2), (1), (1), (1)
Pubmed 2 references available
Quantity 50 µg
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
Catalog No. ABIN197181
253.00 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human STAT5A around the phosphorylation site of Tyrosine 694 (D-G-YP-V-K).
Specificity This antibody detects endogenous levels of total STAT5A around Tyrosine 694.
Purification Affinity Chromatography using epitope-specific immunogen
Alternative Name STAT5 / STAT5A
Background STAT5a protein is a transcription factor activated by hormone and cytokines. Two highly related, but distinct Stat 5 genes (Stat 5a and Stat 5b) were identified in mouse. The amino acid sequences of Stat 5a and Stat 5b show 96% sequence similarity, and both proteins are co expressed in most tissues of both virgin and lactating mice. However, differential accumulation of Stat 5a and Stat 5b mRNA has been reported for both muscle and mammary tissue. Stat 5a is critically involved in a variety of physiological functions, including reproduction, lactation, immune function and somatic growth.
Alternate names: MGF, Mammary gland factor, STAT-5, STAT-5A, Signal transducer and activator of transcription 5A
Gene ID 6776
NCBI Accession NP_003143.2
UniProt P42229
Application Notes Western Blot: 1/500~1/1000. Immunohistochemistry: 1/50~1/100. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS (without Mg2+ and Ca2+), pH 7.4 containing 150mM NaCl, 0.02% Sodium Azide and 50% Glycerol.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store the antibody (in aliquots) at -20°C.
Expiry Date 12 months
Supplier Images
anti-Signal Transducer and Activator of Transcription 5A (STAT5A) (Tyr694) antibody anti-Signal Transducer and Activator of Transcription 5A (STAT5A) (Tyr694) antibody
anti-Signal Transducer and Activator of Transcription 5A (STAT5A) (Tyr694) antibody (2) anti-Signal Transducer and Activator of Transcription 5A (STAT5A) (Tyr694) antibody (Image 2)
Background publications Gouilleux, Wakao, Mundt et al.: "Prolactin induces phosphorylation of Tyr694 of Stat5 (MGF), a prerequisite for DNA binding and induction of transcription." in: The EMBO journal, Vol. 13, Issue 18, pp. 4361-9, 1994 (PubMed).

Dentelli, Del Sorbo, Rosso et al.: "Human IL-3 stimulates endothelial cell motility and promotes in vivo new vessel formation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 163, Issue 4, pp. 2151-9, 1999 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN197181
253.00 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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