You are viewing an incomplete version of our website. Please click to reload the website as full version.

Retinoblastoma 1 antibody (RB1) (Ser780)

Details for Product anti-RB1 Antibody No. ABIN197284, Supplier: Log in to see
Antigen
  • OSRC
  • P105-RB
  • p105-Rb
  • PP110
  • pp110
  • pRb
  • RB
  • Rb
  • Rb-1
  • RB1
  • RB11
  • zgc:154147
Alternatives
anti-Human Retinoblastoma 1 antibody for Immunohistochemistry (Frozen Sections)
Epitope
Ser780
53
50
49
40
35
28
26
19
18
16
16
15
13
9
8
8
7
7
7
6
5
5
5
4
3
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
523
279
236
11
8
7
5
4
4
3
3
2
2
2
Host
Rabbit
448
78
2
Clonality
Polyclonal
Conjugate
This Retinoblastoma 1 antibody is un-conjugated
22
21
21
16
13
13
10
10
7
7
7
7
7
7
7
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
318
240
173
87
80
72
45
26
21
11
10
8
5
5
2
2
2
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Immunogen Synthesized non-phosphopeptide derived from human Rb around the phosphorylation site of serine 780.
Sequence T-L-SP-P-I
Specificity This antibody detects endogenous levels of total Rb protein.
Purification Affinity-chromatography using epitope-specific immunogen
Alternative Name Retinoblastoma-Associated Protein / RB1 (RB1 Antibody Abstract)
Background Synonyms: OSRC, Rb, Retinoblastoma 1, p105-Rb, pRb, pp110
Gene ID 5925
NCBI Accession NP_000312
UniProt P06400
Pathways Cell Division Cycle
Application Notes Western blot (1: 500 - 1: 1000). Immunohistochemistry (1: 50 - 1: 100).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.1 mg/mL
Buffer Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store (in aliquots) at -20 °C.
Supplier Images
 image for anti-Retinoblastoma 1 antibody (RB1) (Ser780) (ABIN197284) anti-Retinoblastoma 1 (RB1) (Ser780) antibody
 image for anti-Retinoblastoma 1 antibody (RB1) (Ser780) (ABIN197284) anti-Retinoblastoma 1 (RB1) (Ser780) antibody (Image 2)
Background publications Roesch, Becker, Meyer, Hafner, Wild, Landthaler, Vogt: "Overexpression and hyperphosphorylation of retinoblastoma protein in the progression of malignant melanoma." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 18, Issue 4, pp. 565-72, 2005 (PubMed).

Huang, Zegarra-Moro, Benson, Tindall: "Androgens repress Bcl-2 expression via activation of the retinoblastoma (RB) protein in prostate cancer cells." in: Oncogene, Vol. 23, Issue 12, pp. 2161-76, 2004 (PubMed).

Kitagawa, Higashi, Jung, Suzuki-Takahashi, Ikeda, Tamai, Kato, Segawa, Yoshida, Nishimura, Taya: "The consensus motif for phosphorylation by cyclin D1-Cdk4 is different from that for phosphorylation by cyclin A/E-Cdk2." in: The EMBO journal, Vol. 15, Issue 24, pp. 7060-9, 1997 (PubMed).