RPA4 antibody (AA 1-260) (HRP)

Catalog No. ABIN1993903

Product Details anti-RPA4 Antibody (HRP)

Target: RPA4 (Replication Protein A4, 30kDa (RPA4))

Binding Specificity: AA 1-260

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPA4 antibody is conjugated to HRP

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Replication protein A 30 kDa subunit protein (1-260AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin^TM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze.
Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for RPA4

Target: RPA4 (Replication Protein A4, 30kDa (RPA4))

Alternative Name: RPA4 (RPA4 Products)

Synonyms: HSU24186 antibody, replication protein A4 antibody, RPA4 antibody

Background:

Background: As part of the alternative replication protein A complex, aRPA, binds single-stranded DNA and probably plays a role in DNA repair. Compared to the RPA2-containing, canonical RPA complex, may not support chromosomal DNA replication and cell cycle progression through S-phase. The aRPA may not promote efficient priming by DNA polymerase alpha but could support DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange.

Aliases: HSU24186 antibody, MGC120333 antibody, MGC120334 antibody, p30 antibody, Replication factor A protein 4 antibody, Replication protein A 30 kDa subunit antibody, RF A antibody, RF-A protein 4 antibody, RFA antibody, RFA4_HUMAN antibody, RP A antibody, RP-A p30 antibody, RPA antibody, RPA4 antibody

UniProt: Q13156

Pathways: Mitotic G1-G1/S Phases, DNA Replication