CHL1 antibody (Cell Adhesion Molecule with Homology To L1CAM (Close Homolog of L1)) (AA 1-1080)

Details for Product anti-CHL1 Antibody No. ABIN1995817, Supplier: Log in to see
Antigen
  • CALL
  • L1CAM2
  • A530023M13Rik
  • AI465420
  • LICAM2
  • cell adhesion molecule L1-like
  • cell adhesion molecule with homology to L1CAM
  • CHL1
  • Chl1
Epitope
AA 1-1080
3
2
2
2
2
1
Reactivity
Human
14
4
1
Host
Rabbit
10
5
1
Clonality
Polyclonal
Conjugate
This CHL1 antibody is un-conjugated
1
Application
ELISA
9
7
1
1
1
1
1
Options
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Immunogen Recombinant Human CHL1 protein (ABIN2215346)
Isotype IgG
Specificity Human CHL1 / CALL
Characteristics Produced in rabbits immunized with purified, recombinant Human CHL1 (rh CHL1, ABIN2215346 NP_006605.2, Met 1-Gln 1080,. Total IgG was purified by Protein A affinity chromatography .
Purification purified by Protein A affinity chromatography
Sterility 0.2 μm filtered
Alternative Name CHL1 (CHL1 Antibody Abstract)
Background Neural cell adhesion molecule L1-like protein, also known as close homolog of L1 (CHL1) is the prototypic member of the CTF / NF-1 family of transcription factors that serve as a novel calcium signaling pathway-responsive transcription factor and is considered as a member of the largest ctf complementation group, consisting of 30 of 126 ctf mutants isolated. CHL1 is a cell adhesion molecule highly related to L1. It contains structure plan of six extracellular C2-type immunoglobulin (Ig) domains followed by five fibronectin typeIII domains linked by a single membrane-spanning region to a short cytoplasmic domain. The extracellular portion of CHL1 is higyly glycosylated and involved them in hemophilic disease.
NCBI Accession NP_006605.2
Application Notes ELISA: 0.5-1 μg/mL
This antibody can be used at 0.5-1 μg/mL with the appropriate secondary reagents to detect Human CHL1. The detection limit for Human CHL1 is 0.0049 ng/well.
Restrictions For Research Use only
Format Liquid
Buffer 0.2 μm filtered solution in PBS with 5 % trehalose
Preservative Without preservative
Handling Advice Avoid repeated freeze-thaw cycles.
Storage 4 °C,-20 °C,-80 °C
Storage Comment This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Expiry Date 12 months
Background publications Alevizopoulos, Dusserre, Rüegg, Mermod: "Regulation of the transforming growth factor beta-responsive transcription factor CTF-1 by calcineurin and calcium/calmodulin-dependent protein kinase IV." in: The Journal of biological chemistry, Vol. 272, Issue 38, pp. 23597-605, 1997

Alevizopoulos, Dusserre, Rüegg, Mermod: "Regulation of the transforming growth factor beta-responsive transcription factor CTF-1 by calcineurin and calcium/calmodulin-dependent protein kinase IV." in: The Journal of biological chemistry, Vol. 272, Issue 38, pp. 23597-605, 1997 (PubMed).