CST7 antibody (Cystatin F (Leukocystatin)) (AA 1-145)

Details for Product anti-CST7 Antibody No. ABIN1995893, Supplier: Log in to see
Antigen
  • CST7
  • LOC100232568
  • cytf
  • CMAP
  • Cmap
  • cystatin F
  • cystatin F (leukocystatin)
  • Cystatin F
  • CST7
  • LOC100232568
  • cytf
  • Cst7
Epitope
AA 1-145
13
3
2
2
1
1
Reactivity
Human
36
35
18
Host
Mouse
32
16
1
Clonality (Clone)
Monoclonal ()
Conjugate
This CST7 antibody is un-conjugated
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
28
21
13
6
6
Options
Supplier
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Supplier Product No.
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Immunogen Recombinant Human CST7 protein (ABIN2002224)
Clone 2F11D9B2
Isotype IgG1
Specificity Human Cystatin-F / Cystatin-7
No cross-reactivity with Human cell lysate (293 cell line) in WB and ELISA.
No Cross-Reactivity Human
Characteristics This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CST7 (rh CST7, ABIN2002224 NP_003641.2, Met 1-His 145,. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Purification purified by Protein A affinity chromatography
Sterility 0.2 μm filtered
Alternative Name CST7 (CST7 Antibody Abstract)
Background The cystatin superfamily members are important natural cysteine protease inhibitors present in a wide variety of organisms and are divided into three classes. Cystatin F, also known as leukocystatin and CMAP (Cystatin-like Metastasis-Associated Protein), is a type 2 cystatin and its expression is limited to hematopoietic cells, with the highest expression levels being observed in monocytes, dendritic cells, and certain types of T-cells. Furthermore, cystatin F mRNA becomes up-regulated during dendritic cell maturation, and thus suggests a specific role of cystatin F in immune regulation. Cystatin F is produced as a dimer, an inactive cathepsin inhibitor which is activated by chemical reduction. In addition, Cystatin F and its homologues have been observed expressing in various human cancer cell lines established from malignant tumors, and thus indicates a new diagnosis and prevention approach of certain human carcinomas metastasis.
NCBI Accession NP_003641.2
Application Notes WB: 2-10 μg/mL
Restrictions For Research Use only
Format Liquid
Buffer 0.2 μm filtered solution in PBS with 5 % trehalose
Preservative Without preservative
Handling Advice Avoid repeated freeze-thaw cycles.
Storage 4 °C,-20 °C,-80 °C
Storage Comment This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Expiry Date 12 months
Supplier Images
Western Blotting (WB) image for anti-Cystatin F (Leukocystatin) (CST7) (AA 1-145) antibody (ABIN1995893) anti-Cystatin F (Leukocystatin) (CST7) (AA 1-145) antibody
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