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Antibodies
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anti-Platelet-Derived Growth Factor alpha Polypeptide (PDGFA) antibody
Platelet-Derived Growth Factor alpha Polypeptide (PDGFA) antibody
| Antigen |
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| Synonyms |
PDGF1, PDGF-A, pdgfa, zgc:100777, PDGFA, pdgf, pdgf1, pdgf-a |
| Clonality |
Polyclonal |
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Host
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Reactivity
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Human (43), Mouse (Murine) (19), Rat (Rattus) (19), Rabbit (16), Chicken (1), Cow (Bovine) (1), Dog (Canine) (1), Horse (Equine) (1), Pig (Porcine) (1), Sheep (Ovine) (1), Zebrafish (Brachydanio rerio) (1)
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Application
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 Alternatives Western Blotting (WB), ELISA, Functional Studies (Func)
Western Blotting (WB) (25), Flow Cytometry (FACS) (18), Immunofluorescence (IF) (18), ELISA (9), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (9), Enzyme Immunoassay (EIA) (8), ELISA (Detection) (4), Functional Studies (Func) (3), Immunoprecipitation (IP) (3), Neutralization (Neut) (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunohistochemistry (IHC) (2), Immunoelectron Microscopy (IEM) (1)
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| Catalog no. |
ABIN205941 |
| Quantity |
100 µg (1 mg/ml) |
| Price |
526.67 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 10 to 15 Business Days |
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Alternative name
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PDGFA
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Swiss-Prot
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P04085
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Immunogen
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Recombinant human PDGF-AA.
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Isotype
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IgG (Matching secondary antibodies)
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Description
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Gene: PDGFA, Standard Gene Symbol: PDGFA, Family: PDGF, Synonyms: PDGFA, PDGF-A, PDGF1, Platelet-derived growth factor a-chain
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Specificity
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Specific for human PDGF-AA (Platelet derived growth factor A chain), a disulphide-linked alpha-chain homodimer and member of the PDGF family, released from platelet alpha-granules following trauma/platelet activation. Naturally occurring active forms of PDGF exist as dimers of two alpha chains (AA), two beta chains (BB), or a combination of both chains (AB), all of which signal through the high-affinity PDGF-Ralpha receptor, and the latter two of which can also signal through the PDGF-Rbeta receptor. PDGFs are potent mitogens for a variety of cells including those of the connective tissue, bone and cartilage, blood and smooth muscle cells, and are involved in several biological processes including chemotaxis, hyperplasia and embryonic neurogenesis. An increased expression of PDGF-AA has been associated with a diverse range of conditions including progression of osteosarcomas, persistent Cytomegalovirus infection in kidney allografts and mediation of IL-13-stimulated lung fibroblast proliferation in asthma
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Application Notes
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ELISA (0.5 µg/ml), Func (0.17 - 0.19 µg/ml), WB (0.1 - 0.2 µg/ml)
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Concentration
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1 mg/ml
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Buffer
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Lyophilized, PBS, pH 7.4., Resuspension: Distilled Water. For long term storage the addition of 0.09% sodium azide is recommended. For functional studies do not add azide.
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Restrictions
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For Research Use only
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Alternatives for antigen "Platelet-Derived Growth Factor alpha Polypeptide (PDGFA)", type "Antibodies"
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Hosts
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Rabbit (38), Mouse (4), Goat (1), Sheep (1)
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Reactivities
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Human (43), Mouse (Murine) (19), Rat (Rattus) (19), Rabbit (16), Chicken (1), Cow (Bovine) (1), Dog (Canine) (1), Horse (Equine) (1), Pig (Porcine) (1), Sheep (Ovine) (1), Zebrafish (Brachydanio rerio) (1)
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Applications
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Western Blotting (WB) (25), Flow Cytometry (FACS) (18), Immunofluorescence (IF) (18), ELISA (9), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (9), Enzyme Immunoassay (EIA) (8), ELISA (Detection) (4), Functional Studies (Func) (3), Immunoprecipitation (IP) (3), Neutralization (Neut) (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunohistochemistry (IHC) (2), Immunoelectron Microscopy (IEM) (1)
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Conjugates
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Biotin (5), Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
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Epitopes
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N-Term (2)
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