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JNK antibody (pThr183, pThr221, pTyr185, pTyr223)

MAPK8 Reactivity: Human, Mouse, Rat, Chicken, C. elegans, Drosophila melanogaster WB, IP Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN210904
  • Target See all JNK (MAPK8) Antibodies
    JNK (MAPK8) (Mitogen-Activated Protein Kinase 8 (MAPK8))
    Binding Specificity
    • 56
    • 27
    • 17
    • 16
    • 16
    • 10
    • 9
    • 8
    • 8
    • 8
    • 8
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 181-190, AA 219-229, pThr183, pThr221, pTyr185, pTyr223
    Reactivity
    • 208
    • 113
    • 98
    • 42
    • 34
    • 20
    • 18
    • 9
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Chicken, C. elegans, Drosophila melanogaster
    Host
    • 195
    • 18
    • 3
    Rabbit
    Clonality
    • 179
    • 37
    Polyclonal
    Conjugate
    • 101
    • 18
    • 16
    • 13
    • 12
    • 10
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    This JNK antibody is un-conjugated
    Application
    • 163
    • 93
    • 55
    • 43
    • 40
    • 39
    • 37
    • 31
    • 19
    • 18
    • 14
    • 12
    • 10
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    Specificity
    Recognizes phosphorylated JNK, Mr 46kD and 55kD. Species cross-reactivity: Human, rat, mouse. Expected to cross-react with Drosophila, C. elegans and chicken based on sequence homology.
    Purification
    Protein A purified
    Immunogen
    Synthetic peptide corresponding to aa181-190 [(MM[pT]P[pY]VVTRY-C)] of human/mouse/rat JNK1 (MAPK 8) and human/mouse/rat JNK2 (MAPK 9). Sequence also matches aa219-229 of human/mouse/rat JNK3.

    Type of Immunogen: Synthetic peptide
    Isotype
    IgG
    Top Product
    Discover our top product MAPK8 Primary Antibody
  • Application Notes
    Approved: IP (1 μg/mL), WB (1 μg/mL)

    Usage: Suitable for use in Immunoprecipitation/Western Blot. Immunoprecipitation/Western Blot: 1 μg/mL. Anti-pan JNK/SAPK1 was used to Immunoprecipitate JNK from lysates of ultraviolet light-treated RAW 264 macrophage. Phosphorylated JNK (T183/Y185) was detected. Phosphorylated JNK was not detected in non-treated lysates.
    Comment

    Target Species of Antibody: Human

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    0.1 M Tris-glycine,  pH 7.4, 0.15 M sodium chloride, 0.05 % sodium azide, before the addition of glycerol to 30 %
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C,-20 °C
    Storage Comment
    4°C or -20°C, Avoid freeze-thaw cycles.
  • Target
    JNK (MAPK8) (Mitogen-Activated Protein Kinase 8 (MAPK8))
    Alternative Name
    MAPK8 / JNK1 / JNK (MAPK8 Products)
    Synonyms
    JNK antibody, JNK-46 antibody, JNK1 antibody, JNK1A2 antibody, JNK21B1/2 antibody, PRKM8 antibody, SAPK1 antibody, SAPK1c antibody, AI849689 antibody, Prkm8 antibody, BSK antibody, BSK/DJNK antibody, Bsk antibody, CG5680 antibody, D-JNK antibody, D-junk antibody, DBSK/JNK antibody, DJNK antibody, DJNK/bsk antibody, Dmel\\CG5680 antibody, JNK/SAPK antibody, Jnk antibody, Junk antibody, SAPKa antibody, c-Jun antibody, dJNK antibody, jnk antibody, T10F20.15 antibody, jnk1 antibody, sapk1 antibody, mapk8 antibody, zgc:112379 antibody, JNKb antibody, mapk8b antibody, mitogen-activated protein kinase 8 antibody, Stress-activated protein kinase jnk-1 antibody, basket antibody, Protein kinase superfamily protein antibody, mitogen-activated protein kinase 8 L homeolog antibody, mitogen-activated protein kinase 8b antibody, mitogen-activated protein kinase 8B-like antibody, MAPK8 antibody, jnk-1 antibody, Mapk8 antibody, bsk antibody, ATMPK8 antibody, mapk8.L antibody, mapk8b antibody, LOC109094263 antibody
    Background
    Name/Gene ID: MAPK8
    Subfamily: MAPK
    Family: Protein Kinase

    Synonyms: MAPK8, JNK, JNK1, JNK1A2, JNK-46, MAP kinase 8, PRKM8, SAPK1, SAPK1c, MAPK 8, C-Jun N-terminal kinase 1, JNK21B1/2, JUN N-terminal kinase
    Gene ID
    5599
    UniProt
    P45983
    Pathways
    MAPK Signaling, WNT Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, S100 Proteins
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