KIR2DL2 antibody (Extracellular Domain)

Catalog No. ABIN211120

Product Details anti-KIR2DL2 Antibody

Target: KIR2DL2 (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 2 (KIR2DL2))

Binding Specificity: Extracellular Domain

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This KIR2DL2 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP)

Specificity: Recognizes the human CD158b cell surface antigen, a 58kD glycoprotein expressed by a subset of NK cells (also known as p58.2 antigen). This antibody also recognizes a 50kD molecule, which is highly homologous to p58.2 in the extracellular domain, but has a shorter cytoplasmic tail. Both molecules are members of the newly described natural killer cell receptor family. CD158b functions as a receptor specific for HLA Class I molecules, including Cw3 and related HLA-C alleles. This antibody can restore the lysis by human NK clones of otherwise lysis protected targets expressing Cw3.

Purification: Purified

Immunogen: NK cell clone E57.

Type of Immunogen: Cells

Isotype: IgG1

Application Details

Application Notes: Approved: Flo (1:10 - 1:50), IP

Usage: Suitable for use in Flow Cytometry and Immunoprecipitation. Flow Cytometry: 1:10-1:50. Use 10 μL to label 1 x10⁶ in 100 μL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.2, 0.5 % BSA, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for KIR2DL2

Target: KIR2DL2 (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 2 (KIR2DL2))

Alternative Name: KIR2DL2 / CD158b (KIR2DL2 Products)

Synonyms: NKAT6 antibody, p58.2 antibody, CD158b antibody, CD158B1 antibody, killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 2 antibody, KIR2DL2 antibody

Background: Name/Gene ID: KIR2DL2
Family: Immunoglobulin

Synonyms: KIR2DL2, CD158B1, Cl-43, CD158k, MHC class I NK cell receptor, NKAT6, NKAT-6, p58 NK receptor CL-43, p58.2, CD158b, CD158b1 antigen

Gene ID: 3803

UniProt: P43627