C1QA antibody

Catalog No. ABIN215655

Product Details anti-C1QA Antibody

Target: C1QA (Complement Component 1, Q Subcomponent, A Chain (C1QA))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This C1QA antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Functional Studies (Func)

Specificity: Recognizes the C-chain of complement C1q (25kD in SDS-PAGE). Useful for detection of C1q-bearing immune complexes in patients with rheumatic disorders. Detects C1q in serum, in serum-C1 and within immune complexes.

Purification: Protein A purified

Immunogen: Purified human complement C1q.

Type of Immunogen: Purified protein

Isotype: IgG1

Application Details

Application Notes: Approved: ELISA, Func, WB (1:100)

Usage: Suitable for use in ELISA, Western Blot and Inhibition experiments (e. g. hemolytic activity). Western Blot: 1:100 (ECL method), Incubation Time 1hr at RT. Inhibition of hemolytic activity: 0.85 μg/mL inhibits 50 % of hemolytic activity in the fluid phase. With C1 bound to immune complexes a dose dependent increase of C1 activity was observed at antibody concentrations of 1.5 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute with 1 mL sterile ddH2O.

Concentration: Lot specific

Buffer: Lyophilized from PBS,  pH 7.4, 0.5 % BSA, 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Reconstitute, aliquot, and store at -20°C.

Target Details for C1QA

Target: C1QA (Complement Component 1, Q Subcomponent, A Chain (C1QA))

Alternative Name: Complement C1QA (C1QA Products)

Synonyms: zgc:109903 antibody, C1QA antibody, AI255395 antibody, C1q antibody, complement C1q A chain antibody, complement component 1, q subcomponent, A chain antibody, complement component 1, q subcomponent, alpha polypeptide antibody, C1QA antibody, c1qa antibody, C1qa antibody

Background: Name/Gene ID: C1QA

Synonyms: C1QA, Complement C1QA

Gene ID: 712

UniProt: P02745

Pathways: Complement System