KCNJ2 antibody (AA 31-130)

Catalog No. ABIN2177159

Product Details anti-KCNJ2 Antibody

Target: KCNJ2 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 2 (KCNJ2))

Binding Specificity: AA 31-130

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNJ2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Kir2.1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-KCNJ2 antibody (ABIN2177159)

Zhao, Xu, Yun, Zhao, Li, Gong, Yuan, Yan, Zhang, Ding, Wang, Zhang, Dong, Xiu, Yang, Liu, Xue, Li: "Chronic obstructive sleep apnea causes atrial remodeling in canines: mechanisms and implications." in: Basic research in cardiology, Vol. 109, Issue 5, pp. 427, (2014) (PubMed).

Target Details for KCNJ2

Target: KCNJ2 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 2 (KCNJ2))

Alternative Name: Kir2.1 (KCNJ2 Products)

Synonyms: KCNJ2 antibody, ATFB9 antibody, HHBIRK1 antibody, HHIRK1 antibody, IRK1 antibody, KIR2.1 antibody, LQT7 antibody, SQT3 antibody, Kir2.1 antibody, Kcnf1 antibody, IRK-1 antibody, potassium voltage-gated channel subfamily J member 2 antibody, potassium inwardly-rectifying channel, subfamily J, member 2 antibody, KCNJ2 antibody, Kcnj2 antibody

Background:

Synonyms: IRK1, LQT7, SQT3, ATFB9, HHIRK1, KIR2.1, HHBIRK1, Inward rectifier potassium channel 2, Cardiac inward rectifier potassium channel, Inward rectifier K(+) channel Kir2.1, IRK-1, hIRK1, Potassium channel, inwardly rectifying subfamily J member 2, KCNJ2

Background: Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium, as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium or cesium.

Gene ID: 3759

UniProt: P63252