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IL17RA Protein (AA 33-320) (His tag)

IL17RA Origin: Human Host: HEK-293 Cells Recombinant >98 % as determined by SDS-PAGE. Active
Catalog No. ABIN2181343
  • Target See all IL17RA Proteins
    IL17RA (Interleukin 17 Receptor A (IL17RA))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Protein Characteristics
    AA 33-320
    Origin
    • 22
    • 9
    • 3
    Human
    Source
    • 16
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This IL17RA protein is labelled with His tag.
    Sequence
    AA 33-320
    Characteristics
    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 34.3 kDa. The protein migrates as 55-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    Purity
    >98 % as determined by SDS-PAGE.
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product IL17RA Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Handling Advice
    Please avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C-8 °C), After reconstitution under sterile conditions for 1 month (4 °C-8 °C) or 3 months (-20 °C to -70 °C).
  • Target
    IL17RA (Interleukin 17 Receptor A (IL17RA))
    Alternative Name
    IL-17 RA (IL17RA Products)
    Synonyms
    IL17R Protein, CANDF5 Protein, CD217 Protein, CDw217 Protein, IL-17RA Protein, hIL-17R Protein, Il17r Protein, AW538159 Protein, Cdw217 Protein, VDw217 Protein, interleukin 17 receptor A Protein, IL17RA Protein, Il17ra Protein
    Background
    Interleukin 17 receptor A (IL17RA) is also known as cluster of differentiation w217 (CDw217), is a pro-inflammatory cytokine secreted by activated T-lymphocytes, belong to ubiquitous type I membrane glycoprotein, and binds with low affinity to interleukin 17A (IL17A). IL 17R mRNA exhibits a broad tissue distribution, and has been detected in virtually all cells and tissues tested . IL 17RA associates with IL 17RC to form a signaling receptor complex for IL 17 and IL 17F . Ligand and IL 17RA ligation promotes T cell activation and the production of IL - 6, G-CSF, SCF, and multiple pro-inflammatory chemokines. Defects in IL17RA are the cause of familial candidiasis type 5 (CANDF5).
    Molecular Weight
    34.3 kDa
    NCBI Accession
    NP_055154
    Pathways
    SARS-CoV-2 Protein Interactome
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