IL17RA Protein (AA 33-320) (His tag)
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- Target See all IL17RA Proteins
- IL17RA (Interleukin 17 Receptor A (IL17RA))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 33-320
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IL17RA protein is labelled with His tag.
- Sequence
- AA 33-320
- Characteristics
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 34.3 kDa. The protein migrates as 55-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Purity
- >98 % as determined by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product IL17RA Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C-8 °C), After reconstitution under sterile conditions for 1 month (4 °C-8 °C) or 3 months (-20 °C to -70 °C).
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- Target
- IL17RA (Interleukin 17 Receptor A (IL17RA))
- Alternative Name
- IL-17 RA (IL17RA Products)
- Synonyms
- IL17R Protein, CANDF5 Protein, CD217 Protein, CDw217 Protein, IL-17RA Protein, hIL-17R Protein, Il17r Protein, AW538159 Protein, Cdw217 Protein, VDw217 Protein, interleukin 17 receptor A Protein, IL17RA Protein, Il17ra Protein
- Background
- Interleukin 17 receptor A (IL17RA) is also known as cluster of differentiation w217 (CDw217), is a pro-inflammatory cytokine secreted by activated T-lymphocytes, belong to ubiquitous type I membrane glycoprotein, and binds with low affinity to interleukin 17A (IL17A). IL 17R mRNA exhibits a broad tissue distribution, and has been detected in virtually all cells and tissues tested . IL 17RA associates with IL 17RC to form a signaling receptor complex for IL 17 and IL 17F . Ligand and IL 17RA ligation promotes T cell activation and the production of IL - 6, G-CSF, SCF, and multiple pro-inflammatory chemokines. Defects in IL17RA are the cause of familial candidiasis type 5 (CANDF5).
- Molecular Weight
- 34.3 kDa
- NCBI Accession
- NP_055154
- Pathways
- SARS-CoV-2 Protein Interactome
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